Results 81 to 90 of about 29,188 (298)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The Threefold Nature of Desire and Its Implications for Ethics and Theology
ReligionsThe study distinguishes three principal forms of desire: bodily desires, desires for perfection, and desires entailed in value-responses. By distinguishing between the self-centered, acquisitive desires for perfection and the inherently self-transcending
Martin Cajthaml
doaj +1 more source
Friendship in the Economy of the Church (Reflections of Fr. Pavel Florensky) [PDF]
Вестник Свято-Филаретовского института, 2016 The present paper is a study of the notion of friendship (or philic love) as viewed by Pavel Florensky in his work The Pillar and Ground of the Truth. The notion of friendship is Florensky’s response to the theory of the ascetic eros seen as a path to ...
Tatyana Panchenko
doaj
Actitudes hacia el amor en relaciones románticas de jóvenes universitarios
Praxis & Saber, 2017 El presente estudio muestra un análisis de identificación de las tipologías del amor más sobresalientes en las relaciones de pareja, a través de la Escala de Actitudes Amorosas (Hendrick y Hendrick), la cual explora los seis tipos de amor propuestos por ...
Brenda Liz Rocha Narváez +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Les Cahiers des dix, 2009 La convivialité est une valeur fondamentale chez les Dix. Alors qu’ils forment une Société sur la base de leur attachement à l’histoire du Québec et de l’Amérique française, leurs moments de complicité les plus intenses se manifestent autour d’une bonne table où la gastronomie trouve des adeptes.
openaire +1 more source
Love, Anger, and Racial Injustice [PDF]
, 2019 Luminaries like Martin Luther King, Jr. urge that Black Americans love even those who hate them. This can look like a rejection of anger at racial injustice.
Cherry, Myisha
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Dyadisches Coping und Partnerschaftszufriedenheit bei verschiedenen Liebesstilen
Journal of Family Research, 2015 In the last forty years, many attempts were made to approach the complexity of “love” as a research topic. In 1973, Lee developed a typology of six different love styles: Eros (passionate love), Ludus (game-playing love), Storge (friendship love), Pragma
Simona Gagliardi +2 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source