Results 71 to 80 of about 5,203 (247)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Verbum VitaeThe article examines the Johannine foundation of the Encyclical Deus Caritas Est. It shows how Benedict XVI drew heavily on the Augustinian exegesis of the Johannine literature (with a particular focus on the First Epistle of John). The analysis follows
Isacco Pagani
doaj +1 more source
The Public and Social Character of Love in the History of Sociological Thought
Paedagogia Christiana, 2018 The starting point of this paper is represented by the research carried out by the study group of Social-One (Iorio, 2014; 2015; Araújo et al., 2015; Araújo et al., 2016; Martins, Cataldi, 2016), which recognised a public dimension and not only the ...
Silvia Cataldi
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 1999 SLOTT-AGAPE is a new collaboration project among international partners from England, France, Germany, Switzerland and Italy thta intends top perform microlensing observations by using the M31 galaxy as target to search for ...
Rubano, C. +43 more
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Katecheza podstawą rozwoju agape według Klemensa Aleksandryjskiego
Vox Patrum, 1990 Titus Flavius Clemens war ein hervorragender Vertreter der katechetlschen Schule in Alezandrien.
Józef Grzywaczewski
doaj
The Threefold Nature of Desire and Its Implications for Ethics and Theology
ReligionsThe study distinguishes three principal forms of desire: bodily desires, desires for perfection, and desires entailed in value-responses. By distinguishing between the self-centered, acquisitive desires for perfection and the inherently self-transcending
Martin Cajthaml
doaj +1 more source