Results 101 to 110 of about 5,203 (247)
Romance and Repetition: Testing the Limits of Love
Following on from my previous work in Romance Writing on the “deep structures” of romance, this article speculates further on the temporality of romantic love: in particular, the problems posed by repetition. In the course of my discussion, I move from a
Lynne Pearce
doaj
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
This is tape 2 of the Agape series that was recorded on 25 October 1997 of Landon Brady ...
Saunders, Landon Brady
core
Hans Urs Von Balthasar sur l’amour chrétien : erôs et/ou agapè ?
L'amour chrétien, amour trinitaire communiqué au croyant pour qu'il aime Dieu, lui-même et son prochain, consiste-t-il exclusivement dans l'agapè, ou bien peut-il intégrer – et si oui comment – d'autres dimensions de l'amour humain : philia, erôs ?
Jean-Noël Dol
doaj +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Charles Darwin was unimpressed by the natural theology of his time, owing to his observations of suffering in nature and, famously, the particularly elegant viciousness of parasitoid wasps (Ichneumonidae). Presented here is a theological reflection, from
Andrew P. Nosal
doaj +2 more sources
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source

