Comprehensive molecular characterization of cfDNA as predictive and monitoring biomarkers in advanced gastric cancer receiving immunotherapy. [PDF]
Fang J +7 more
europepmc +1 more source
Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer +6 more
wiley +1 more source
Research progress on the role of AGC kinase family in bladder cancer. [PDF]
Su P, Yang Y, Luo X, Zhang N, Zheng H.
europepmc +1 more source
In a population‐based cohort in Japan, HBV reactivation‐related events were observed after HBsAg seroclearance, including one virologically confirmed hepatic flare occurring spontaneously without chemotherapy or immunosuppression. These findings indicate that HBsAg seroclearance does not always represent complete viral eradication, supporting the need ...
Kazumi Yamasaki +7 more
wiley +1 more source
Sintilimab Plus Nanoparticle Polymeric Micellar Paclitaxel and S-1 as First-Line Treatment in HER2-Negative Advanced Gastric Cancer: A Real-World Study. [PDF]
Cao YQ +7 more
europepmc +1 more source
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera +9 more
wiley +1 more source
Retraction: Modeling and Experimental Analyses Reveals Signaling Plasticity in a Bi-Modular Assembly of CD40 Receptor Activated Kinases. [PDF]
PLOS One Editors.
europepmc +1 more source
Neuroticism, Internalizing Psychopathology, and Affective Reactions to Thought Content in Daily Life
ABSTRACT Introduction This study examined affective reactions to thought content (TC) in daily life and the influence of neuroticism and internalizing symptoms. Methods Community young adults (N = 119; n = 80 with elevated depression/anxiety) completed assessments of neuroticism, internalizing symptoms, and daily diary measures of TC and positive ...
Henry R. Cowan +5 more
wiley +1 more source
A vast stem-progenitor cell pool, richly vascular system, and hybrid ossification drive the daily centimeter-scale elongation of bony antlers. [PDF]
Ba H +22 more
europepmc +1 more source

