Results 121 to 130 of about 155,399 (295)

Understanding the Impact of the Sirtuin 1 (SIRT1) Gene on Age-related Macular Degeneration: A Comprehensive Study

Nigerian Postgraduate Medical Journal
Age-related macular degeneration (AMD) is a prevalent and incurable condition affecting the central retina and posing a significant risk to vision, particularly in individuals over the age of 60.
Saranya Velmurugan, Rashmi Pauline, Gurudeva Chandrashekar, Langeswaran Kulanthaivel, Gowtham Kumar Subbaraj   +4 more
doaj   +1 more source

Transcriptome changes in age-related macular degeneration

BMC Medicine, 2012
Age-related macular degeneration (AMD) is a debilitating, common cause of visual impairment. While the last decade has seen great progress in understanding the pathophysiology of AMD, the molecular changes that occur in eyes with AMD are still poorly ...
Whitmore S Scott, Mullins Robert F
doaj   +1 more source

Secretory autophagy and epithelial‐to‐mesenchymal transition in cadaveric AMD samples: Novel pathways in disease progression

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine the presence of secretory autophagy and epithelial–mesenchymal transition (EMT) in the macular retinal pigment epithelium (RPE) of human cadaver eyes with different forms of age‐related macular degeneration (AMD). Methods Human cadaver macula samples representing dry and wet AMD, as well as age‐matched controls, were ...
Iswariyaraja Sridevi Gurubaran, Ali Koskela, Hanna Heloterä, Kai Kaarniranta   +3 more
wiley   +1 more source

Interventions for submacular haemorrhage: A systematic review and network meta‐analysis of controversies—On behalf of the Spanish Vitreo‐Retinal Society (SERV)

Acta Ophthalmologica, EarlyView.
Abstract Purpose This systematic review aims to evaluate and synthesize the existing literature on the interventions used for submacular haemorrhage (SMH), highlighting the controversies and differences in clinical practice. Method A systematic review was conducted following the PRISMA guidelines.
Salvador Pastor‐Idoate, Pablo Redruello‐Guerrero, Laura de Juan Hernández, Gregorio Benites‐Narcizo, Mario Rivera‐Izquierdo, José García‐Arumí, José Carlos Pastor Jimeno   +6 more
wiley   +1 more source

Low‐contrast visual acuity versus low‐luminance visual acuity in choroideremia

Clinical and Experimental Optometry, EarlyView., 2020
Clinical relevance Choroideremia is a progressive X‐linked inherited rod‐cone dystrophy. Patients present with nyctalopia and progressive visual field loss, but visual acuity remains well preserved early on. This study showed that low‐luminance visual acuity may be a useful clinical outcome measure during earlier disease stages.
Laura J Wood, Jasleen K Jolly, Colm D Andrews, Iain R Wilson, Doron Hickey, Jasmina Cehajic‐Kapetanovic, Robert E MacLaren   +6 more
wiley   +1 more source

SD‐OCT‐based biomarkers in predicting treatment outcomes of macular oedema secondary to retinal vein occlusion treated with anti‐VEGF therapy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the role of spectral domain optical coherence tomography (SD‐OCT)‐based biomarkers in predicting treatment response of macular oedema (MO) secondary to retinal vein occlusion (RVO) to anti‐vascular endothelial growth factor (VEGF) therapy.
Ken K. Tsang, Vivian W. K. Hui, Christopher M. K. Pang, Ziqi Tang, Dawei Yang, Truong X. Nguyen, Shaheeda Mohamed, Timothy Y. Y. Lai, Carol Y. Cheung, Simon K. H. Szeto   +9 more
wiley   +1 more source

Choroidal vascular hyperpermeability patterns in central serous chorioretinopathy correlate with microperimetry: CERTAIN study report 4

Acta Ophthalmologica, EarlyView.
Abstract Purpose This report evaluates the association of three distinct leakage patterns of choroidal vascular hyperpermeability (CVH) on indocyanine green angiography (ICGA), previously correlated with disease chronicity, with retinal sensitivity measured by microperimetry in central serous chorioretinopathy (CSC): unifocal indistinct signs of ...
Jennifer M. Chang‐Wolf, Laurenz J. B. Pauleikhoff, Chabelie Ruiters, Annette C. Moll, Reinier O. Schlingemann, Elon H. C. van Dijk, Roselie M. H. Diederen, Camiel J. F. Boon   +7 more
wiley   +1 more source

Yleistyvä silmänpohjan ikärappeuma : Kyselytutkimus Oulussa, Haukiputaalla ja Kiimingissä työskentelevien optikoiden silmänpohjan ikärappeumaan liittyvistä tiedoista, kokemuksista ja toiminnasta [PDF]

, 2010
Tutkimuksen tarkoituksena oli kartoittaa optikoiden tietoja ja kokemuksia silmänpohjan ikärappeumasta ja sen yleisyydestä. Lisäksi tarkoituksena oli selvittää, miten optikot toimivat seuloessaan silmänpohjan ikärappeumaa sekä heidän ajatuksiaan ...
Juutinen, Anna, Lohi, Katri
core  

Real‐world outcomes of aflibercept 8 mg in patients previously treated for neovascular age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age‐related macular degeneration (nAMD). Methods This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti‐VEGF therapies at Sahlgrenska University Hospital between February 2024 and ...
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund   +5 more
wiley   +1 more source

Fluid/function correlation using AI‐based quantification versus central subfield thickness in treatment‐naïve and pre‐treated patients with neovascular AMD in a real‐world setting

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between best‐corrected visual acuity (BCVA) and quantitative macular fluid volumes, compared to central subfield thickness (CST) in treatment‐naïve and previously treated patients with active neovascular age‐related macular degeneration (nAMD).
Anna Eidenberger, Gregor S. Reiter, Virginia Mares, Sophie Frank‐Publig, Philipp Fuchs, Magdalena Baratsits, Markus Gumpinger, Georg Faustmann, Alexandra Miere, Catherine Creuzot‐Garcher, Ulrike Scheschy, Laurent Kodjikian, Vincent Gualino, Benjamin Wolff, Stefan Sacu, Ursula Schmidt‐Erfurth   +15 more
wiley   +1 more source