Results 141 to 150 of about 205,027 (361)

Transcriptome changes in age-related macular degeneration

BMC Medicine, 2012
Age-related macular degeneration (AMD) is a debilitating, common cause of visual impairment. While the last decade has seen great progress in understanding the pathophysiology of AMD, the molecular changes that occur in eyes with AMD are still poorly ...
Whitmore S Scott, Mullins Robert F
doaj   +1 more source

Early stages of age-related macular degeneration: an immunofluorescence and electron microscopy study. [PDF]

, 1993
Theo L. van der Schaft, Cornelia M. Mooy, W.C. de Bruijn, P T de Jong   +3 more
openalex   +1 more source

A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

Nature Communications, 2019
Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly in the developed world. While treatment is effective for the neovascular or “wet” form of AMD, no therapy is successful for the non-neovascular or “dry” form ...
J. Handa, Catherine Bowes Rickman, A. Dick, M. Gorin, Joan W. Miller, C. Toth, M. Ueffing, M. Zarbin, L. Farrer   +8 more
semanticscholar   +1 more source

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao, Linxin Wei, Huan Chen, Yan Luo, Youxin Chen, Zhikun Yang   +5 more
wiley   +1 more source

Prevalence of age related macular degeneration in persons aged 50 years and over resident in Australia. [PDF]

, 1993
R. A. Mitchell
openalex   +1 more source

Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou, Li Dong, Yu‐Hang Yang, Yuan He, Xiao‐Zhen Wang, Han‐Qing Zhao, Rui‐Heng Zhang, Jost B. Jonas, Wen‐Bin Wei   +8 more
wiley   +1 more source

Drusen in age-related macular degeneration [PDF]

, 1994
I H Chisholm
openalex   +1 more source

Outsourced eye care in the Finnish capital region: Switching from fee‐for‐service to bundled payment model

Acta Ophthalmologica, EarlyView.
Abstract Purpose The demand for specialised eye care has quadrupled over the last two decades, driven by an aging population and the advent of new treatments. This surge has led to increased outsourcing by the Helsinki and Uusimaa Hospital District (HUS) Eye Hospital, initially relying on a fee‐for‐service model. This model, however, has been marked by
Susanna Moisander, Jukka Ari Olavi Moilanen, Hans Henrik Konstantin Backström, Olga Marjasova, Marko Juhani Myöhänen, Taina Pauliina Nykänen, Mikko Juhani Pietilä, Paulus Torkki   +7 more
wiley   +1 more source

Age-related macular degeneration: experimental and emerging treatments

Clinical Ophthalmology, 2009
Jean Pierre Hubschman, Shantan Reddy, Steven D SchwartzJules Stein Eye Institute, Department of Ophthalmology, University of California, David Geffen School of Medicine, Los Angeles, California, USAPurpose: This essay reviews the experimental treatments ...
Jean Pierre Hubschman, Shantan Reddy, Steven D Schwartz   +2 more
doaj  

The Relationship between Complements and Age-Related Macular Degeneration and Its Pathogenesis

Journal of Ophthalmology
Age-related macular degeneration is a retinal disease that causes permanent loss of central vision in people over the age of 65. Its pathogenesis may be related to mitochondrial dysfunction, inflammation, apoptosis, autophagy, complement, intestinal ...
Liyuan Chu, Chaoran Bi, Caiming Wang, Hongyan Zhou   +3 more
doaj   +1 more source