Results 261 to 270 of about 207,426 (323)

Deficiency of 2‐Oxoglutarate Carrier (Slc25a11) Drives RPE Epithelial‐to‐Mesenchymal Transition and Exacerbates Subretinal Fibrosis in Neovascular Age‐Related Macular Degeneration

Aging Cell, Volume 24, Issue 12, December 2025.
The diagram shows that OGC deficiency leads to mitochondrial dysfunction, which activates the PI3K/AKT/Slug pathway and triggers epithelial‐mesenchymal transition (EMT) in retinal pigment epithelial cells. This process promotes myofibroblast accumulation and subretinal fibrosis in laser‐induced CNV, contributing to the progression of AMD.
Mo Wang, Feng‐Juan Gao, Wenyi Tang, Boya Lei, Fangyuan Hu, Jun Ma, Srinivas R. Sadda, Ram Kannan, Parameswaran G. Sreekumar, Gezhi Xu   +9 more
wiley   +1 more source

Pharmacotherapy for Age-Related Macular Degeneration

Journal of Ophthalmic & Vision Research, 2008
Hamid Ahmadieh
doaj  

Kynurenine pathway metabolites as potential biomarkers in age-related macular degeneration: an ELISA-based prospective study. [PDF]

Int J Retina Vitreous
Dundar A, Cetik Yildiz S.
europepmc   +1 more source

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

Acta Ophthalmologica, Volume 103, Issue 8, Page 998-1009, December 2025.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao, Linxin Wei, Huan Chen, Yan Luo, Youxin Chen, Zhikun Yang   +5 more
wiley   +1 more source

Japanese clinical guidelines for neovascular age-related macular degeneration. [PDF]

Jpn J Ophthalmol
Iida T, Gomi F, Yasukawa T, Yamashiro K, Honda S, Maruko I, Kataoka K, Japanese Retina and Vitreous Society Guidelines Committee for Neovascular Age-Related Macular Degeneration.   +7 more
europepmc   +1 more source

Home Optical Coherence Tomography Monitoring for Neovascular Age-Related Macular Degeneration: Transformative Technology or Cool Toy? [PDF]

Ethan T. Willis, Judy E. Kim, Eric W. Schneider   +2 more
openalex   +1 more source

Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans

Acta Ophthalmologica, Volume 103, Issue 8, Page 919-928, December 2025.
Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou, Li Dong, Yu‐Hang Yang, Yuan He, Xiao‐Zhen Wang, Han‐Qing Zhao, Rui‐Heng Zhang, Jost B. Jonas, Wen‐Bin Wei   +8 more
wiley   +1 more source

Retinal Vessel Coronal Displacement in Intermediate Age-Related Macular Degeneration. [PDF]

J Clin Med
Parravano M, Fragiotta S, Polito MS, Varano M, Querzoli G, Rossi T.   +5 more
europepmc   +1 more source

Comparison of treat-and-extend (T&E) dosing regimens and visual outcomes in the ARIES and ALTAIR studies of intravitreal aflibercept (IVT-AFL) in neovascular age-related macular degeneration (nAMD)

, 2020
Paul Mitchell, Frank G. Holz, Philip Hykin, Edoardo Midena, Annabelle A. Okada, Eric H. Souied, Kanji Takahashi, Sébastian Wolf, Helmut Allmeier, George Ι. Lambrou, Thomas Schmelter, Masahito Ohji   +11 more
openalex   +1 more source

Generative mathematical modelling to demonstrate virtual simulations of neovascular age related macular degeneration

, 2017
David C. Hoyle, Tariq Aslam
openalex   +2 more sources