Results 111 to 120 of about 17,828,039 (353)
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Pediatric hospitalizations associated with respiratory syncytial virus (RSV) and influenza, and the frequency of asthma as a secondary diagnosis [PDF]
Background: There is uncertainty about the burden of severe outcomes associated with RSV and influenza in children. Methods: We have applied previously developed methodology to estimate the rates of influenza and RSV-associated hospitalizations with different diagnoses in different age subgroups of US children between the 2003-04 through the 2009-10 ...
arxiv
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Liaison Old Age Psychiatry services (LOAP) have begun to emerge in the UK and further development of the service is supported by the latest health policies.
E. B. Mukaetova-Ladinska+10 more
doaj +1 more source
ANALISIS PENGARUH LIKUIDITAS, LEVERAGE, DAN PROFITABILITAS TERHADAP LABA [PDF]
Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh likuiditas, leverage dan profitabilitas terhadap laba yang dimiliki oleh PT.Gajah Tunggal Tbk. selama periode 1997-2008.Pengujian hipotesis ini menggunakan analisis regresi linier berganda,
Budiarti, Age Estri, Virda, Yudilla
core
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston+7 more
wiley +1 more source
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
General functions for human survival and mortality [PDF]
General functions for human survival and mortality may support a possibility of general mechanisms in human ageing. We discovered that the survival and mortality curves could be described very simply and accurately by the Weibull survival function with age-dependent shape parameter.
arxiv
EPIDEMIOLOGIC AND IMMUNOLOGIC SIGNIFICANCE OF AGE DISTRIBUTION OF ANTIBODY TO ANTIGENIC VARIANTS OF INFLUENZA VIRUS [PDF]
Fred M. Davenport+2 more
openalex +1 more source