Results 151 to 160 of about 17,828,039 (353)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Interaction of ASK1 and the β-amyloid precursor protein in a stress-signaling complex

Neurobiology of Disease, 2007
The amyloid precursor protein (APP) is a type I transmembrane protein translocated to neuronal terminals, whose function is still unknown. The C-terminus of APP mediates its interaction with cellular adaptor and signaling proteins, some of which signal ...
Veronica Galvan, Surita Banwait, Patricia Spilman, Olivia F. Gorostiza, Alyson Peel, Marina Ataie, Danielle Crippen, Wei Huang, Gurleen Sidhu, Hidenori Ichijo, Dale E. Bredesen   +10 more
doaj  

Jewish Life in the Middle Ages. Israel Abrahams [PDF]

, 1898
Joseph K. Arnold
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Relationship of autistic traits and the severity of fear of the COVID-19 pandemic in the general population

Frontiers in Psychiatry
BackgroundThe aim of the study was to investigate the level of fear of the COVID-19 pandemic and to detect a possible correlation between the autistic traits and the level of fear and to learn about other factors that may affect the level of fear ...
Dominika Bieczek, Adrianna Ściślicka, Agnieszka Bobowska, Filip Tomsia, Krzysztof Maria Wilczyński, Krzysztof Maria Wilczyński, Małgorzata Janas-Kozik, Małgorzata Janas-Kozik   +7 more
doaj   +1 more source

The Promise of the Christ-Age in Recent Literature. William Eugene Mosher [PDF]

, 1913

openalex   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Earth's Earliest Ages, and Their Connection with Modern Spiritualism and Theosophy. G. H. Pember [PDF]

, 1886

openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Des Basilius aus Achrida, Erzbischofs von Thessalonich, bisher unedierte Dialoge. Josef SchmidtRegula Antiqua Fratrum et Sororum seu Tertii Ordinis Sancti Francisci. Paul SabatierThe Development of Doctrine from the Early Middle Ages to the Reformation. John S. BanksThe Reformation Dawn. F. V. N. PainterLa controverse de l'apostolicité des églises de France au XIXe siècle. A. HoutinThe Crime of Christendom; Or, The Eastern Question from Its Origin to the Present Time. Daniel Seelye Gregory [PDF]

, 1902
J. W. Moncrief
openalex   +1 more source