Results 111 to 120 of about 49,659,107 (249)

Biological and Physiological Changes in Adolescence: Sociocultural Impact on Adolescent Sexual Attitude and Reproductive Health

Journal of Psychosexual Health
This study examines the sociocultural impact of adolescent bio-physiological development on sexual health. By using three key metrics: sexual intercourse by age 15, self-reported sexually transmitted infections (STIs) symptoms, and condom use at last ...
Jegede Tovia, Otioro Jane Godwin, Saccoh Abdul, Okpanachi Favour Ojoanemile, Kamara Marie, Jimoh Sherifat Olamide   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Clustering of cell-type-specific annotation for uterine leiomyoma, age at first sexual intercourse, and lifetime number of sexual partners over histone marks.

Clustering of cell-type-specific annotation for uterine leiomyoma, age at first sexual intercourse, and lifetime number of sexual partners over histone marks.
Changfeng Xiao (9986113), Xia Jiang (210366), C. Scott Gallagher (5613056), Danielle Rasooly (10004357), Xueyao Wu (15413859), Cynthia Casson Morton (18501467), Xunying Zhao (15413862)   +6 more
core   +1 more source

Age at menarche and first sexual intercourse. A cross-sectional study of 17-year old Danish women

, 1997
The age at menarche and first intercourse was analyzed from data obtained from a questionnaire sent to 1500 17 year-old randomly selected Danish women (76% responded). The average age at menarche was 13.37 years (SD: 1.24).
Kragstrup, J, Larsen, S B
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Bayesian spatial analysis of demographic survey data [PDF]

In this paper we analyze the spatial patterns of the risk of unprotected sexual intercourse for Italian women during their initial experience with sexual intercourse. We rely on geo-referenced survey data from the Italian Fertility and Family Survey, and
Riccardo Borgoni, Francesco Billari
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Survival Analysis of Age at First Marriage and Age at First Sexual Intercourse among Women in Rural Ethiopia

, 2016
Age at first marriage and first sex has important implications for gender relations and the organization of family life in societies. Age at marriage is of particular interest because it marks the transition to adulthood in many societies; the point at ...
Yihenew Mitiku
core  

Contraceptive non-use and emergency contraceptive use at first sexual intercourse among nearly 12 000 Scandinavian women

, 2017
Introduction. The aim of this study was to describe recent patterns of contraceptive use at first sexual intercourse and to examine whether selected factors are associated with non-use and emergency contraceptive pill use at first sexual intercourse ...
Kjaer, SK, Nygard, M, Munk, Christian, Guleria, S, Munk, C, Juul, KE, Guleria, Sonia, Juul, Kirsten E., Kjær, Susanne K., Hansen, BT, Arnheim-Dahlström, Lisen, Nygård, Mari, Liaw, K-L, Liaw, Kai Li, Hansen, Bo T., Arnheim-Dahlstrom, L   +15 more
core   +1 more source