Results 141 to 150 of about 41,803,081 (273)

Mendelian randomisation of age at menarche for non-lipid cardiometabolic traits at age 18 y among females in ALSPAC.

, 2018
Mendelian randomisation of age at menarche for non-lipid cardiometabolic traits at age 18 y among females in ALSPAC.
Kaitlin H. Wade (611034), Joshua A. Bell (5692670), Nicholas J. Timpson (111625), David Carslake (313427), Rebecca C. Richmond (538687), Ryan J. Langdon (5692673), George Davey Smith (82619), Emma E. Vincent (426053), Michael V. Holmes (256443)   +8 more
core   +1 more source

Two Novel ACTC1 Variants Cause Arthrogryposis Multiplex Congenita

Clinical Genetics, Volume 110, Issue 5, Page 584-589, November 2026.
We report on two individuals with arthrogryposis multiplex congenita who were heterozygous for ACTC1 missense variants (NM_005159.5; c.325G>A, p.Glu109Lys and c.650A>C, p.Lys217Thr) and provide a characterization of these variants through in vitro studies.
Lauren Kerr, Pierre Moffatt, Lauren Hyer, Sarah Nossov, Noémi Dahan‐Oliel, Frank Rauch   +5 more
wiley   +1 more source

Assessing causal links between age at menarche and adolescent mental health: a Mendelian randomisation study

BMC Medicine
Background The timing of puberty may have an important impact on adolescent mental health. In particular, earlier age at menarche has been associated with elevated rates of depression in adolescents.
Adrian Dahl Askelund, Robyn E. Wootton, Fartein A. Torvik, Rebecca B. Lawn, Helga Ask, Elizabeth C. Corfield, Maria C. Magnus, Ted Reichborn-Kjennerud, Per M. Magnus, Ole A. Andreassen, Camilla Stoltenberg, George Davey Smith, Neil M. Davies, Alexandra Havdahl, Laurie J. Hannigan   +14 more
doaj   +1 more source

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Association between age at menarche and infertility in Tabari cohort population: a population-based case-control study

BMC Research Notes
Objective There are conflicting results regarding the association between age at menarche (AAM) and infertility in different nations. Thus, this study aimed to determine this relationship in a cohort of northern Iranian population (Tabari Cohort Study ...
Marzieh Zamaniyan, Mina Esmaeili, Sepideh Peivandi, Shamim Khorshidian, Mobina Gheibi, Monirolsadate Hosseini Tabaghdehi, Mahmood Moosazadeh, Erfan Ghadirzadeh   +7 more
doaj   +1 more source

Further Observations on Age of the Menarche [PDF]

BMJ, 1950
D C, WILSON, I, SUTHERLAND
openaire   +2 more sources

Associations of age at menarche with adiposity and blood pressure at age 18 y among females in ALSPAC.

, 2018
Associations of age at menarche with adiposity and blood pressure at age 18 y among females in ALSPAC.
Kaitlin H. Wade (611034), Joshua A. Bell (5692670), Nicholas J. Timpson (111625), David Carslake (313427), Rebecca C. Richmond (538687), Ryan J. Langdon (5692673), George Davey Smith (82619), Emma E. Vincent (426053), Michael V. Holmes (256443)   +8 more
core   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Early- Life Determinants of the Age at Menarche. [PDF]

, 2016
Menarche, the first menstrual period, is a recognizable marker of puberty. The timing of menarche has important public health ramifications because an early age at menarche is associated with breast and endometrial cancers, obesity, type II diabetes ...
Jansen, Erica Christine
core  

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, Volume 13, Issue 56, 9 October 2026.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source