Results 121 to 130 of about 41,887,776 (253)
PLoS ONEMenopause is a key period in women's lives associated with major physiological changes. Early menopausal age has been linked to a range of adverse outcomes. Estrogen has been found to increase levels of thyroid binding proteins in the blood; however, its
Durmalouk Kesibi +3 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto +9 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background Risk‐reducing salpingo‐oophorectomy is the standard intervention for prevention of tubo‐ovarian carcinoma in women with pathogenic BRCA1/2 variants, yet the optimal timing remains clinically challenging, particularly for BRCA2 carriers.
Olga Zikan Dubova +4 more
wiley +1 more source
Lactobacillus johnsonii attenuates ovarian aging by remodeling the gut–ovary axis
iMetaOmics, EarlyView.Aging is accompanied by a reduced abundance of L. johnsonii and ovarian decline. Supplementation with L. johnsonii elevates microbial IPA production via the LdhA enzyme and commensal bacteria. IPA activates the AhR/YAP signaling axis, promoting YAP nuclear translocation and inducing the expression of downstream target genes CYR61 and CTGF. This cascade
Jiamin He +16 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
iNew Medicine, EarlyView.This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin +10 more
wiley +1 more source
Toxic metals and the menopause
, 2004 Toxicity of chemicals and environmental pollutants may be expressed differently in women than in men. Until recently, most research involved men. With the initiation of studies on the effects of environmental pollutants in women, there is increasing ...
Vahter, M,, Berglund, M,, Akesson, A
core +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Using data from 6674 middle‐aged and older Chinese adults in the China Health and Retirement Longitudinal Study (CHARLS), this study investigated the association between the triglyceride glucose‐waist height ratio (TyG‐WHtR) index and cardiometabolic multimorbidity (CMM).
Lingling Li +8 more
wiley +1 more source
The Age of Menopause in Medieval Europe
, 2021 Medieval sources from the 6th through the 15th centuries were reviewed to determine the probable age at menopause. By far the most frequently cited age at menopause is 50 years, approximately equivalent to the age currently being reported for the mid ...
Diers, Carol Jean, Amundsen, Darrel W
core
Transperineal Ultrasound in Chronic Pelvic Pain: A Systematic Review
Journal of Clinical Ultrasound, EarlyView.Graphical abstract illustrating the systematic review process and highlighting key pelvic floor musculature (PFM) alterations detected by transperineal ultrasound (TPU) in patients with chronic pelvic pain (CPP) and associated conditions. These findings provide insights to enhance understanding and management of CPP.
Giulia Paoni Saccone +10 more
wiley +1 more source