Results 101 to 110 of about 1,962,777 (258)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Chemical Composition and Age of the Metal-Poor Halo Star BD +17^\circ 3248
, 2002 We have combined new high-resolution spectra obtained with the Hubble Space Telescope (HST) and ground-based facilities to make a comprehensive new abundance analysis of the metal-poor, halo star BD +17^\circ 3248.
Bell R. A. +34 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
THE AGE COMPOSITION OF ANOPHELES FLUVIATILIS AND ITS SEASONAL VARIATION IN HORMOZGAN PROVINCE
Iranian Journal of Public Health, 1999 This investigation was carried out in Koveh village Siahow district, Hormozgan province, from spring 1997 to the end of fall 1998. Anophele fluviatilis is highly exophilic in this region, so it was not possible to collect a good number of An. Floviatilis
H. Edalat +2 more
doaj
Clinical and Translational ScienceChronological age has been the standard for quantifying the aging process. While it is simple to quantify it cannot fully discern the biological variability of aging between individuals. The growing body of interest in this variability of human aging has
Radin Alikhani +3 more
doaj +1 more source
Decomposing the change in labour force indicators over time [PDF]
In this paper we study changes in the size and the composition of the labour force in five OECD countries from 1983 through 2000. We apply a recent decomposition method to quantify the components of the change over time in the crude labour force rate and
Alexia Prskawetz +3 more
core
Calibration of White Dwarf cooling sequences: theoretical uncertainty
, 2002 White Dwarf luminosities are powerful age indicators, whose calibration should be based on reliable models. We discuss the uncertainty of some chemical and physical parameters and their influence on the age estimated by means of white dwarf cooling ...
Clemens J. C. +16 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Citation: 'age composition' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14428 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source