Results 181 to 190 of about 2,561,520 (316)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Association Between Changes in Maternal Age Distribution and Hypertensive Disorders of Pregnancy in the United States, 2011-2021. [PDF]

Circ Popul Health Outcomes
Hughes ZH, Hughes LL, Petito LC, Grobman WA, Khan SS, Huang X.   +5 more
europepmc   +1 more source

Bacterial age distribution in soil - Generational gaps in adjacent hot and cold spots. [PDF]

PLoS Comput Biol, 2022
Borer B, Or D.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Nonlinear growth generates age changes in the moments of the frequency distribution: the example of height in puberty

, 2008
Higher moments of the frequency distribution of child height and weight change with age, particularly during puberty, though why is not known. Our aims were to confirm that height skewness and kurtosis change with age during puberty, to devise a model to
Cortina-Borja, M, Kelly, FP, Pan, HQ, Sandhu, J, Cole, TJ   +4 more
core  

On the distribution of population by ages

Proceedings of the Physico-Mathematical Society of Japan. 3rd Series, 1938
openaire   +2 more sources

Normalization of Seasonality and Age Distribution of Pediatric RSV Infection Following the Pandemic Disruption in the Netherlands. [PDF]

Open Forum Infect Dis
Rave N, de Bruijne MEM, Stellato RK, Bannier MAGE, Weinberger DM, Löwensteyn YN, Wildenbeest JG, Bont LJ, Surveillance of Pediatric REspiratory Admissions in Dutch hospitals (SPREAD) Study Group .   +8 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Prevalence, age-distribution, and impact on management of acne in patients on upadacitinib for inflammatory bowel disease: insights from a single-center survey. [PDF]

Crohns Colitis 360
Spencer EA, Smyth M, Cices A, Mercurio A, Helmus D, Ungaro RC, Dubinsky MC.   +6 more
europepmc   +1 more source

The shifting age distribution of people with HIV using antiretroviral therapy in the United States. [PDF]

AIDS, 2022
Althoff KN, Stewart CN, Humes E, Zhang J, Gerace L, Boyd CM, Wong C, Justice AC, Gebo KA, Thorne JE, Rubtsova AA, Horberg MA, Silverberg MJ, Leng SX, Rebeiro PF, Moore RD, Buchacz K, Kasaie P.   +17 more
europepmc   +1 more source