Results 191 to 200 of about 2,561,520 (316)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Population structure, age distribution and sex composition of long-tailed gorals in Jangsudae, Seoraksan National Park, Republic of Korea. [PDF]

Biodivers Data J
Lim S, Banjade M, Kim KY, Lim A, Park Y.
europepmc   +1 more source

Identifying the changing age distribution of opioid-related mortality with high-frequency data. [PDF]

PLoS One, 2022
Paul LA, Li Y, Leece P, Gomes T, Bayoumi AM, Herring J, Murray R, Brown P.   +7 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Death distribution methods for estimating adult mortality [PDF]

TThe General Growth Balance (GGB) and Synthetic Extinct Generations (SEG) methods have been widely used to evaluate the coverage of registered deaths in developing countries.
Kenneth Hill, Yoonjoung Choi, Danzhen You   +2 more
core  

Statistical Evidence for Bimodal Age Distribution in Pediatric Orchiopexy: Support for Congenital and Acquired Cryptorchidism Subtypes. [PDF]

Cureus
Ohashi K, Yoshizawa S, Kogure K.
europepmc   +1 more source

Impact of subgroup-specific heterogeneities and dynamic changes in mortality rates on forecasted population size, deaths, and age distribution of persons receiving antiretroviral treatment in the United States: a computer simulation study. [PDF]

Ann Epidemiol, 2023
Kasaie P, Stewart C, Humes E, Gerace L, Hyle EP, Zalla LC, Rebeiro PF, Silverberg MJ, Rubtsova AA, Rich AJ, Gebo K, Lesko CR, Fojo AT, Lang R, Edwards JK, Althoff KN.   +15 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Age Distribution of the Onset of Esotropia [PDF]

British Journal of Ophthalmology, 1953
openaire   +2 more sources

Age distribution and etiological characteristics of patients hospitalized with mechanical ocular trauma from 2017 to 2021. [PDF]

BMC Ophthalmol
Xiong Y, Ren X, Jiang X, Wang R, Xu B, Lin L, Liu H.   +6 more
europepmc   +1 more source