Results 91 to 100 of about 1,989,859 (272)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Performance of Artificial Intelligence Models Designed for Automated Estimation of Age Using Dento-Maxillofacial Radiographs—A Systematic Review

Diagnostics
Automatic age estimation has garnered significant interest among researchers because of its potential practical uses. The current systematic review was undertaken to critically appraise developments and performance of AI models designed for automated ...
Sanjeev B. Khanagar, Farraj Albalawi, Aram Alshehri, Mohammed Awawdeh, Kiran Iyer, Barrak Alsomaie, Ali Aldhebaib, Oinam Gokulchandra Singh, Abdulmohsen Alfadley   +8 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Gait features fusion for efficient automatic age classification

IET Computer Vision, 2018
Far from the camera, image resolution is significantly degraded and person cannot cooperate with the acquisition equipment. So, the classical intrusive biometrics approach could not be applied.
Nabila Mansouri, Mohammed Aouled Issa, Yousra Ben Jemaa   +2 more
doaj   +1 more source

Nonparametric Calibration for Age Estimation

Journal of the Royal Statistical Society Series C: Applied Statistics, 2002
SUMMARY A method is proposed for the calibration of a continuous random variable when the dependent variables are a combination of continuous and categorical, and the model between the controlling variables and calibrated variable is empirically derived.
Lucy, David, Ackroyd, R. G., Pollard, M.
openaire   +1 more source

Mandatory Retirement Rules and the Retirement Decisions of University Professors in Canada [PDF]

We examine the impact of mandatory retirement on the retirement decisions of professors in Canada using administrative data. We find that the age distributions of professors at universities without mandatory retirement and those at universities with ...
Casey Warman, Christopher Worswick
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

MAPLES: A general method for the estimation of age profiles from standard demographic surveys (with an application to fertility) [PDF]

In this paper we present MAPLES (Method for Age Profiles Longitudinal EStimation), a general method for the estimation of age profiles that uses standard micro-level demographic survey data. The aim is to estimate smoothed age profiles and relative risks
Francesco Billari, Roberto Impicciatore
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Mental Foramen in Prediction of Age [PDF]

Journal of Clinical and Diagnostic Research, 2015
Tanuj Kanchan, Kewal Krishan
doaj   +1 more source