Results 91 to 100 of about 10,300 (213)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

MRI Application in Quantification of Epiphyseal Development in the Wrist and Bone Age Estimation of Han Male Adolescents in East China

open access: yesFayixue Zazhi
ObjectiveTo investigate the value of wrist MRI in bone age estimation for male adolescents in Shanghai, Zhejiang and Jiangsu.MethodsA total of 124 Han male adolescents aged 6.0 to 18.0 years from Shanghai, Zhejiang and Jiangsu were selected as subjects ...
ZHOU Zhi-lu   +9 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Using the method of inverse growth calculations to determine the age composition of catches for certain species of marine commercial fish

open access: yesИзвестия ТИНРО
New method for constructing size-and-age keys is proposed and tested on the data on size composition of yellowfin sole in commercial catches in the Patience Bay in 1950–2024, with the age of fish determined using the inverse growth calculations ...
A. O. Zolotov
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Clinical Applicability of Various Digital Softwares Used in Forensic Odontology for Age Estimation Using Teeth on Cone-beam Computed Tomography Imaging: A Systematic Review and Meta-Analysis

open access: yesJournal of Medical Physics
Background and Aim: Forensic odontology plays a crucial role in age estimation and personal identification, especially in cases where only dental remains are available. In a similar context, various newer innovations in digital software are a key tool to
Gandikota Kartheek   +8 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

An Evaluation of Four Radiological Methods for Dental Age Estimation in the Montenegrin Population

open access: yesDiagnostics
Objectives: In this study, we aimed to evaluate the accuracy of four radiological methods for dental age estimation and to test which method is the most reliable in Montenegrin children.
Tina Pajevic   +6 more
doaj   +1 more source

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