Results 151 to 160 of about 9,169,898 (343)

Predictive role of loneliness on mortality before the age 85 years among mid- to later-life adults in the United States: a 10-year retrospective cohort study

Epidemiology and Psychiatric Sciences
Aims Loneliness is a common public health concern, particularly among mid- to later-life adults. However, its impact on early mortality (deaths occurring before reaching the oldest old age of 85 years) remains underexplored.
Hui-Ying Fan, Mu-Rui Zheng, Qinge Zhang, Sha Sha, Yuan Feng, Zhaohui Su, Teris Cheung, Gabor S Ungvari, Lloyd Balbuena, Yu-Tao Xiang   +9 more
doaj   +1 more source

The Internet as a Diversion and Destination [PDF]

, 2011
Presents survey findings about trends since 2000 in why Americans go online by age, gender, race/ethnicity, education, and income.
Lee Rainie
core  

Transcription Factors and Aging [PDF]

Molecular Medicine, 1997
openaire   +3 more sources

Intestinal Absorption and Hepatic Uptake of Radioactive Vitamin B12 in Various Age Groups and the Effect of Intrinsic Factor Preparations

, 1956
George B. Jerzy Glass, Alton Goldbloom, Linn J. Boyd, Roger W. Laughton, Sidney Rosen, Marilyn Rich   +5 more
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Feeling good in old age: factors explaining health-related quality of life. [PDF]

Health Qual Life Outcomes, 2018
Alcañiz M, Solé-Auró A.
europepmc   +1 more source

Risk factors of esophageal cancer in Turkmen Sahra of Iran [PDF]

, 2007
Present study was carried out in three years' duration (2002-2004) to investigate the risk factors of esophageal cancer in Iranian Turkmens (Northeast of Iran; where the esophageal cancer is the most common world wide).
Besharat, S., Kalavi, K., Moradi, A., Qujeq, D.   +3 more
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Association between age factors and strategies for promoting participation in gastric and colorectal cancer screenings. [PDF]

BMC Cancer, 2018
Hamashima C, Sano H.
europepmc   +1 more source