Results 221 to 230 of about 26,120,112 (307)

Epidemiology and associated factors of childhood chalazion in China: a seven-year, hospital-based, multicenter, cross-sectional study. [PDF]

J Pediatr (Rio J)
Liu C, Wang X, Feng G, Zhang C, Li L, Jiang J.   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Determinants of Low Birth Weight in Ghana: Analysis of the 2022 Demographic and Health Survey. [PDF]

Health Sci Rep
Ofori MA, Mensah DK, Asamoah T, Ofori MF.   +3 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Global Patterns and Temporal Trends in Modifiable Risk Factors Among Women of Childbearing Age, 1990-2021: A Systematic Analysis from the Global Burden of Disease Study. [PDF]

Int J Womens Health
Xu Q, Zhang H, Chen B, Xie Z, Lin Q, Zhao Y, She G, Zhong F, Li J.   +8 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Comprehensive Analysis of Atrial Fibrillation/Atrial Flutter Burden in the United States and the European Union: A Comparison and Assessment of Trends and Risk Factors. [PDF]

J Cardiovasc Dev Dis
Jancic P, Milutinovic S, Stanojevic D.
europepmc   +1 more source