An Ecological Risk Model for Early Childhood Anxiety: The Importance of Early Child Symptoms and Temperament [PDF]
Childhood anxiety is impairing and associated with later emotional disorders. Studying risk factors for child anxiety may allow earlier identification of at-risk children for prevention efforts.
Briggs-Gowan, Margaret J. +3 more
core +3 more sources
Growth factors, aging and age-related diseases [PDF]
Simple organisms including yeast and flies with mutations in the IGF-1 and Tor-S6K pathways are dwarfs, are highly protected from toxins, and survive up to 3 times longer. Similarly, dwarf mice with deficiencies in the growth hormone-IGF-I axis are also long lived and protected from diseases.
Priya, Balasubramanian, Valter D, Longo
openaire +2 more sources
Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. [PDF]
Discrete time survival analysis was used to assess the age-specific association of event-related oscillations (EROs) and CHRM2 gene variants on the onset of regular alcohol use and alcohol dependence.
Almasy, Laura +20 more
core +2 more sources
Changes in ponderal index and body mass index across childhood and their associations with fat mass and cardiovascular risk factors at age 15 [PDF]
Background: Little is known about whether associations between childhood adiposity and later adverse cardiovascular health outcomes are driven by tracking of overweight from childhood to adulthood and/or by vascular and metabolic changes from childhood ...
A Fraser +29 more
core +7 more sources
The predictive value of the CONUT score combined with the A2DS2 scale for post-ischemic stroke infection [PDF]
Background/Aim. Stroke-associated infection is the most common and most serious complication of ischemic stroke (IS), which is the most important cause of death and disability in humans.
Zhang Yongqing, Zhang Wei, Zhou Yiwu
doaj +1 more source
Prehypertension and hypertension prevalence and risk factors among adult population in Republic of Serbia: A cross-sectional study [PDF]
Background/Aim. Prehypertension and hypertension are an important public health problem worldwide and although they can be modified, they are often a risk for cardiovascular diseases.
Šipetić-Grujičić Sandra +4 more
doaj +1 more source
Melatonin Alters Age-Related Changes in Transcription Factors and Kinase Activation [PDF]
Male mice were fed 40 ppm melatonin for 2 months prior to sacrifice at age 26 months, and compared with both 26 and 4 month-old untreated controls. The nuclear translocation of NF-κB increased with age in both brain and spleen and this was reversed by ...
A Jagota +35 more
core +4 more sources
Clinical and laboratory status in Parkinson’s disease patients with and without polyneuropathy [PDF]
Background/Aim. The etiology of polyneuropathy (PNP) in patients with Parkinson’s disease (PD) is unclear, and there is a possible association between levodopa therapy, hyperhomocysteinemia, and PNP development due to methylation processes involving ...
Popović Sanela +4 more
doaj +1 more source
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has enabled better prognosis for patients with peritoneal surface malignancies. However, in older age groups, short -and long-term outcomes are still perceived as poor.
Cheng Ernest +8 more
doaj +1 more source
Minor neurological dysfunction in children aged 5 to 7 [PDF]
Background/Aim. Assessment of minor neurological dysfunction (MND) provides information about a child's neurological condition which helps to identify the vulnerability of the child to the development of motor impairment, difficulties in learning or ...
Galić Maja +4 more
doaj +1 more source

