Results 71 to 80 of about 26,204,504 (362)

Introduction and reconciliation of the ROS and aging paradoxes [PDF]

arXiv, 2017
This paper suggests that aging is influenced synthetically by pro-aging factors such as ROS and anti-aging factors such as protective responses. The anti-aging effect may be side effects of retrograde responses motivated against adverse circumstances. ROS may be more closely correlated with metabolism rather than aging.
arxiv  

The Relationship between Accretion Disc Age and Stellar Age and its Consequences for Proto-Stellar Discs [PDF]

, 2011
We show that for young stars which are still accreting and for which measurements of stellar age, disc mass and accretion rate are available, nominal disc age (Disc Age = Disc Mass / Accretion Rate) is approximately equal to the stellar age, at least within the considerable observational scatter.
arxiv   +1 more source

Changes in ponderal index and body mass index across childhood and their associations with fat mass and cardiovascular risk factors at age 15 [PDF]

, 2010
Background: Little is known about whether associations between childhood adiposity and later adverse cardiovascular health outcomes are driven by tracking of overweight from childhood to adulthood and/or by vascular and metabolic changes from childhood ...
A Fraser, A Must, AC Skinner, Adrian V. Hernandez, Andy R. Ness, AS Singh, CG Owen, CL Ogden, Debbie A. Lawlor, DS Freedman, DSL Gardner, E Falaschetti, E Sundblom, George Davey Smith, J Golding, Jennifer Logue, Kate Tilling, KK Ong, KK Ong, KK Ong, L Dubois, Laura D. Howe, LD Howe, Li Benfield, Naveed Sattar, R Sinha, RR Kipping, StataCorp, TJ Cole, Y Wang   +29 more
core   +3 more sources

A Geriatric Patient: Age Is Not a Factor [PDF]

International Journal of Dentistry, 2011
Objective.A patient presented to the dental office expressing dissatisfaction with the appearance of his teeth, and as a result, of his smile. Our objective was to satisfy his initial chief complaint: “I don't like how my teeth look when I smile.”Methodology.Upon completing all initial exams and consultations, an esthetic dental treatment plan was ...
Lisa Klodnitskaya, Michele M. Harutunian, Santiago Mareque Buenos, Mark S. Wolff, Denise Estafan   +4 more
openaire   +2 more sources

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

FEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause, Musalula Sinkala, Raj Ramesar   +2 more
wiley   +1 more source

Influences on diet quality in older age: the importance of social factors

Age and Ageing, 2016
Background poor diet quality is common among older people, but little is known about influences on food choice, including the role of psychosocial factors at this age.
I. Bloom, M. Edwards, K. Jameson, H. Syddall, E. Dennison, C. Gale, J. Baird, C. Cooper, A. Aihie Sayer, S. Robinson   +9 more
semanticscholar   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

Personalized Age Progression with Aging Dictionary [PDF]

arXiv, 2015
In this paper, we aim to automatically render aging faces in a personalized way. Basically, a set of age-group specific dictionaries are learned, where the dictionary bases corresponding to the same index yet from different dictionaries form a particular aging process pattern cross different age groups, and a linear combination of these patterns ...
arxiv  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Age spreads in star forming regions? [PDF]

, 2008
Rotation periods and projected equatorial velocities of pre-main-sequence (PMS) stars in star forming regions can be combined to give projected stellar radii. Assuming random axial orientation, a Monte-Carlo model is used to illustrate that distributions of projected stellar radii are very sensitive to ages and age dispersions between 1 and 10 Myr ...
arxiv   +1 more source