Results 211 to 220 of about 122,362 (305)

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

Development of gut microbiota composition in captive Asian elephants: a year-long analysis. [PDF]

Sci Rep
Klinhom S, Kunasol C, Sriwichaiin S, Kerdphoo S, Chattipakorn N, Chattipakorn SC, Thitaram C.   +6 more
europepmc   +1 more source

The chemokine receptor‐like fourth extracellular loop of the apelin receptor differentially regulates apelin and elabela binding and signalling

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Apelin and Elabela are endogenous ligands of the apelin receptor (apelin receptor/APJ), a GPCR involved in cardiovascular regulation and body fluid homeostasis. The human receptor contains a conserved disulfide bridge linking the N‐terminal domain to extracellular loop 3 (ECL3) via Cys19 and Cys281, forming a structural ...
Chloé Bonef, Hela Bouhsine, Carine Huynh, Marion Chaigneau, Steven Dubois, Mikel Garcia‐Marcos, Catherine Llorens‐Cortes, Denis Servent, Philippe Robin, Hervé Nozach, Isabel Alves, Xavier Iturrioz   +11 more
wiley   +1 more source

Risk Factors for and Prevalence of Failure of Passive Transfer of Immunity in Calves on Dairy Farms in Türkiye. [PDF]

Vet Med Sci
Sağlam N, Topal O, Biçer P, Uzabacı E, Gençoğlu H, Mee JF, Batmaz H.   +6 more
europepmc   +1 more source

An experimental approach to assess the combined effects of multiple stressors on a large vertebrate species

Conservation Biology, EarlyView.
Abstract The design of experiments to investigate the combined effects of multiple stressors requires exposing target organisms to multiple combinations of stressor doses. Concurrent manipulation of stressors is often infeasible with wildlife, but long‐lasting health effects allow individual health to be used as an integrator of prior stressor exposure.
Enrico Pirotta, Catriona M. Harris, Lori H. Schwacke, Len Thomas, Jason B. Allen, Aaron A. Barleycorn, Marco Casoli, Jonathan Crossman, Laura Aichinger Dias, Laura Engleby, Erin LaBrecque, Jenny A. Litz, Katherine A. McHugh, Patrick J. O. Miller, Michael J. Moore, Theoni Photopoulou, Brian M. Quigley, Cynthia R. Smith, Brandon L. Southall, Todd R. Speakman, Ryan Takeshita, Christina N. Toms, Randall S. Wells, Eric S. Zolman, Peter L. Tyack   +24 more
wiley   +1 more source

Effects of age and feeding protocols on the metabolic and physiological condition of unweaned calves during and after long-distance transport. [PDF]

Ir Vet J
Siegmann S, van Dijk LL, Field NL, Sayers G, Sugrue K, van Reenen CG, Bokkers EAM, Conneely M.   +7 more
europepmc   +1 more source

Effects of Age and Diet on Rumen and Blood Components of the Young Calf

Journal of Dairy Science, 1965
D.E. Otterby, J.W. Rust
openaire   +1 more source

Informing elephant management through demographic snapshots

Conservation Science and Practice, EarlyView.
Understanding demography is vital for managing species successfully; however, for elephants, traditional surveys are both costly and labor‐intensive. This study presents a cost‐effective method for estimating age structures of savannah elephants in southern Africa, revealing how water provisioning, density dependence, and fertility control influence ...
Ryan M. Huang, Stuart L. Pimm, Cornelius J. Louw, Robert A. R. Guldemond   +3 more
wiley   +1 more source

Congenital Ocular Findings in an Antillean Manatee (Trichechus manatus manatus). [PDF]

Vet Med Sci
Attademo FLN, Oliveira REM, Luna FO, Val HGPD, Melo LIDS, Silva LHSD, Bezerra B, Sá FB.   +7 more
europepmc   +1 more source

Squamoid Eccrine Ductal Carcinoma: Case Series of a Rare, Potentially Aggressive Skin Cancer Associated With Immunosuppression

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Squamoid Eccrine Ductal Carcinoma (SEDC) is a rare cutaneous adenexal carcinoma first described in 1997. It has distinct biphasic features on histology which commonly result in misdiagnosis as Bowen disease or cutaneous squamous cell carcinomas (cSCC) if diagnostic skin biopsies are too superficial. This may lead to a delay in diagnosis. It is
Xiang Li Tan, Pooja Patel, Jeva Cernova, Sarah Hogan, Jason Thomson, Efthymios Hadjimichael, Sharanpal Jeetle, Dorota Markiewicz, Michael Sheaff, Nilukshi Wijesuriya, Mark Hawthorne, Graeme Moir, Matthew Stodell, Kapil Bhargava, Suchitra Chinthapalli, Catherine A. Harwood   +15 more
wiley   +1 more source