Temporal discrimination: Mechanisms and relevance to adult-onset dystonia [PDF]
Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired sequential stimuli are perceived as ...
Beck, Rebecca +7 more
core +1 more source
The Relationship between Early Disability Onset and Education and Employment [PDF]
The early onset of disability (at birth through young adulthood) can affect a person's employment outcomes in myriad ways. In addition to the direct effect of disability on employment, early onset of disability likely affects the acquisition of education
Elaine Maag, Pamela J. Loprest
core +1 more source
The Impact of Drug and Alcohol Consumption and Socio-demographic Variables on the Age of First Selling Sex among Iranian Female Sex Workers [PDF]
Background: A significant proportion of Female Sex Workers (FSWs) as a vulnerable population begin sellingsex at an early age, which may lead the person to develop sexually-transmitted infections (STIs) and humanimmunodeficiency virus (HIV).
Mahboobeh Mousavi-Ramezanzade +3 more
doaj +1 more source
Early nurturing experiences, self-compassion, hyperarousal and scleroderma the way we relate to ourselves may determine disease progression [PDF]
<p>Scleroderma is a rare, painful and complex autoimmune connective tissue disease that can lead to death. The physiology of symptom onset and progression and the psychological aspects of living with this chronic disease have been studied fairly ...
Hicks, Richard E., Kearney, Karen
core +1 more source
Late onset of Huntington's disease [PDF]
Twenty-five patients with late-onset Huntington's disease were studied; motor impairment appeared at age 50 years or later. The average age at onset of chorea was 57.5 years, with an average age at diagnosis of 63.1 years.
Myers, R. H. +7 more
core
A family history of breast cancer will not predict female early onset breast cancer in a population-based setting [PDF]
: BACKGROUND: An increased risk of breast cancer for relatives of breast cancer patients has been demonstrated in many studies, and having a relative diagnosed with breast cancer at an early age is an indication for breast cancer screening.
A Lucassen +36 more
core +8 more sources
A next-generation sequencing approach to identify gene mutations in early-and late-onset hypertrophic cardiomyopathy patients of an Italian cohort [PDF]
Sequencing of sarcomere protein genes in patients fulfilling the clinical diagnostic criteria for hypertrophic cardiomyopathy (HCM) identifies a disease-causing mutation in 35% to 60% of cases.
Autore, Camillo +11 more
core +1 more source
BackgroundPerceptions of cigar products' harmfulness and addictiveness in youth are associated with subsequent cigar product initiation, but their association on the age of initiation of cigar product use is unknown.MethodsThe association of perceptions ...
Baojiang Chen +7 more
doaj +1 more source
Early‐onset Alzheimer's disease explained by polygenic risk of late‐onset disease?
Early‐onset Alzheimer's disease (AD) is highly heritable, yet only 10% of cases are associated with known pathogenic mutations. For early‐onset AD patients without an identified autosomal dominant cause, we hypothesized that their early‐onset disease ...
William G. Mantyh +21 more
doaj +1 more source
The Age of Onset of Anxiety Disorders
The objective was to estimate the age of onset (AOO) for all anxiety disorders and for specific subtypes. Gender differences in the AOO of anxiety disorders were examined, as were the influence of study characteristics on reported AOOs.Seven electronic databases were searched up to October 2014, with keywords representing anxiety disorder subtypes, AOO,
Legerstee, J.S. +6 more
openaire +7 more sources

