Results 91 to 100 of about 69,152 (263)

Three years results of the use of spectacle lenses Stellest® with embedded rings of high-spherical microlenses for the myopia control in children

Российский офтальмологический журнал
Purpose: to study and compare the dynamics of the spherical equivalent (SE) of refraction and the anterior-posterior length (AL) of the eye in children who wore spectacle lenses Stellest® with embedded rings of high-spherical microlenses Stellest® during
O. V. Proskurina, E. P. Tarutta, N. A. Tarasova, S. V. Milash, S. G. Harutyunyan, G. A. Markosyan   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Reference values for the six-minute pegboard and ring test in healthy adults in Brazil

Jornal Brasileiro de Pneumologia
Objective: To determine reference values for the six-minute pegboard and ring test (6PBRT) in healthy adults in Brazil, correlating the results with arm length, circumference of the upper arm/forearm of the dominant arm, and the level of physical ...
Vanessa Pereira Lima, Fabiana Damasceno Almeida, Tania Janaudis-Ferreira, Bianca Carmona, Giane Amorim Ribeiro-Samora, Marcelo Velloso   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Late Holocene history of the Shkhelda Glacier, Northern Caucasus, according to remote sensing, dendrochronology and cosmogenic (¹⁰Be) dating of moraines

Лëд и снег
The position of the Shkhelda valley glacier front (Elbrus region, 43.18N, 42.64 E) for the period from the 1880s to 2022 was reconstructed based on interpretation of aerial and satellite images and old maps.
O. N. Solomina, I. S. Bushueva, V. Jomelli   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The symbolic role of the ring in the Viking Age

Historical bulletin
в статье рассматривается семантическое значение кольца в эпоху викингов в Скандинавии. Цель – проанализировать специфическое скандинавское восприятие колец и связанные с ними культурные, бытовые и религиозные практики на основании сравнения текстов источников и данных современной исторической науки. Методы – при анализе литературы используются историко-
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Age of Jack mackerel Trachrus murphyi (Carangidae) using daily growth rings in sagittae otoliths

Gayana, 2019
Growth of Jack mackerel (Trachurus murphyi) was estimated using daily growth rings in fish collected in central-south Chile from 2004 to 2011. The von Bertalanffy growth curve at length for both sexes (n=210 individuals) is FL = 75*[1-e-0.16(t+0 ...
Lilian Cisterna, Hugo Arancibia
doaj