Results 191 to 200 of about 3,504,476 (344)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Stages of objective memory impairment are associated with accelerated brain aging. [PDF]

Sci Rep
Flo BK, Skouras S, Matziorinis AM, Bashevkin T, Gaser C, Koelsch S.   +5 more
europepmc   +1 more source

THE TRANSITION OF AGING HEALTH PRACTITIONERS TO RETIREMENT STAGE : A comparison between Doctors and Nurses in Sweden and Ghana

, 2019
Francisca Assamany, Adom Naomi
openalex   +1 more source

Early Stages Arc Volcanism in the Eastern Himalayan Synstaxis, Yarlung Zongbo Suture Zone, Tibet, China: New Zircon Age, Hf Isotopic, Geochemical Constrains and Implication for the Tectonic Evolution History of Neo‐Tethys [PDF]

, 2015
Yuan Li, Jingsui Yang, Zhiqin Xu, Hanwen Dong, Zhao Liu, Jian Zhang   +5 more
openalex   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Multi-Stage transcriptomic dissection identifies key molecular determinants of chicken follicular development. [PDF]

Poult Sci
Bai Y, Li H, Ji X, Wang W, Shao T, Chu Q, Yuan R, Wang Y, Liu L.   +8 more
europepmc   +1 more source

MNEMOTECHNIQUE AS AN INNOVATIVE TOOL FOR FORMING SPEECH COMPETENCE OF CHILDREN OF SENIOR PRESCHOOL AGE: FEATURES OF THE FORMATIVE STAGE OF RESEARCH

Inna Nikolaesku, Yu. O. Solovei, Viktoria Bondar   +2 more
openalex   +2 more sources

Risk Factors and Quality of Life in Patients With Geographic Atrophy, a Late Stage of Age-Related Macular Degeneration: Findings From the Korea National Health and Nutrition Examination Survey [PDF]

Yeji Kim, Yun Tae Kim, Mingui Kong, Jae Hui Kim   +3 more
openalex   +1 more source

A Randomized Phase II Trial of First-Line Treatment with Gemcitabine, Erlotinib, or Gemcitabine and Erlotinib in Elderly Patients (Age ≥70 Years) with Stage IIIB/IV Non-small Cell Lung Cancer [PDF]

, 2011
Thomas E. Stinchcombe, Amy H. Peterman, Carrie B. Lee, Dominic T. Moore, Jennifer L. Beaumont, Daniel S. Bradford, Kamal Bakri, Mark Taylor, Jeffrey M. Crane, Garry Schwartz, Thomas A. Hensing, Edwin McElroy, Harvey B. Niell, Harry Harper, Sridhar Pal, Mark A. Socinski   +15 more
openalex   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source