Results 171 to 180 of about 5,400,886 (261)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Age Structure, Growth, and Survival Rates of an Insular Population of <i>Hemidactylus turcicus</i>. [PDF]

Ecol Evol
Altunışık A, Kurtul D, Gül Ç, Boran B, Tosunoğlu M.   +4 more
europepmc   +1 more source

The impact of age structure and vaccine prioritization on COVID-19 in West Africa. [PDF]

Infect Dis Model, 2022
Taboe HB, Asare-Baah M, Yesmin A, Ngonghala CN.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Temporal evolution of Sow herd age structure and its impact on the performance of Spanish commercial farms. [PDF]

Porcine Health Manag
Sanz-Fernández S, Díaz-Gaona C, Simões J, Casas-Rosal JC, Alòs N, Tusell L, Quintanilla R, Rodríguez-Estévez V.   +7 more
europepmc   +1 more source

Should we adjust health expenditure for age structure on health systems efficiency? A worldwide analysis. [PDF]

Health Econ Rev, 2023
Santos JV, Martins FS, Pestana J, Souza J, Freitas A, Cylus J.   +5 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

An inevitably ageing world: analysis on the evolutionary pattern of age structure in 200 countries. [PDF]

R Soc Open Sci
Ma J, Chen Q, Chen X, Fan J, Li X.
europepmc   +1 more source

Fractal-fractional age-structure study of omicron SARS-CoV-2 variant transmission dynamics. [PDF]

Partial Differ Equ Appl Math, 2022
Addai E, Zhang L, Asamoah JKK, Preko AK, Arthur YD.   +4 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source