Results 71 to 80 of about 1,192,855 (302)

Patients Aged 80 Years or Older are Encountered More Potentially Inappropriate Medication Use

Chinese Medical Journal, 2016
Background:Polypharmacy and potentially inappropriate medications (PIMs) are prominent prescribing issues in elderly patients. This study was to investigate the different prevalence of PIM use in elderly inpatients between 65–79 years of age and 80 years
Li Mo, Ding Ding, S. Pu, Qin-Hui Liu, Hong Li, B. Dong, Xiaoyan Yang, Jinhan He   +7 more
semanticscholar   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Is Spinal Surgery Safe for Elderly Patients Aged 80 and Above? Predictors of Mortality and Morbidity in an Asian Population [PDF]

Neurospine, 2019
Objective We aimed to determine the 2-year mortality and morbidity rates following spine surgery in elderly patients (age ≥80 years) and to study the associated risk factors.
Joshua Yuan-Wang Tan, Arun-Kumar Kaliya-Perumal, Jacob Yoong-Leong Oh   +2 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Physical frailty prediction model for the oldest old

Revista Latino-Americana de Enfermagem, 2018
Objective: to present a physical frailty prediction model for oldest old users of primary health care, according to clinical variables. Method: cross-sectional study with proportional stratified sample of 243 oldest old subjects.
Jacy Aurelia Vieira de Sousa, Maria Helena Lenardt, Clóris Regina Blanski Grden, Luciana Kusomota, Mara Solange Gomes Dellaroza, Susanne Elero Betiolli   +5 more
doaj   +1 more source

Factors predicting a successful post-discharge outcome for individuals aged 80 years and over

International Journal of Integrated Care, 2012
Introduction and background The early post-discharge period is a vulnerable time for older patients with complex care requirements. This paper identifies factors predicting a self-reported successful post-discharge outcome for patients aged 80 years and ...
L. Bragstad, M. Kirkevold, D. Hofoss, Christina Foss   +3 more
semanticscholar   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Exploring an informed decision-making framework using in-home sensors: older adults’ perceptions

Journal of Innovation in Health Informatics, 2014
Background Sensor technologies are designed to assist independent living of older adults. However, it is often difficult for older adults to make an informed decision about adopting sensor technologies.Objective To explore Bruce’s framework of informed ...
Jane Chung, Blaine Reeder, Amanda Lazar, Jonathan Joe, George Demiris, Hilaire J. Thompson   +5 more
doaj   +1 more source

APPLICABILITY OF DIET QUALITY ASSESSMENT INSTRUMENTS IN THE OLDEST-OLD: AMPAL STUDY

Geriatrics, Gerontology and Aging, 2020
OBJECTIVE: To compare the applicability of the 2006 Brazilian Ministry of Health food guide questionnaire Como ter uma alimentação saudável (QGAS — How to have a healthy diet) and the 2013 National Health Survey healthy eating questionnaire (QA-PNS) for ...
Valéria Baccarin Ianiski, Flávia Picoli Gheno, Ângelo José Gonçalves Bós   +2 more
doaj   +1 more source

Comparison of single-agent chemotherapy and targeted therapy to first-line treatment in patients aged 80 years and older with advanced non-small-cell lung cancer

OncoTargets and Therapy, 2015
Purpose The aim of this study was to compare single-agent chemotherapy with targeted therapy in initial treatment and to explore a better choice of treatment for patients aged 80 years and older with advanced non-small-cell lung cancer (NSCLC).
Qianqian Zhang, Zhehai Wang, Jun Guo, Liyan Liu, Xiao Han, Minmin Li, S. Fang, X. Bi, N. Tang, Yang Liu   +9 more
semanticscholar   +1 more source