Results 91 to 100 of about 14,824,921 (380)

Improving care for cancer-related and other forms of lymphoedema in low- and middle-income countries: a qualitative study

BMC Health Services Research, 2022
Background Lymphoedema is a common, distressing and debilitating condition that can be related to cancer and its treatment or other conditions. Little is known about current practices in the diagnosis, assessment and management of lymphoedema in low- and
Eric Torgbenu, Tim Luckett, Mark Buhagiar, Cecilia Mauricio Requena, Jane L. Phillips   +4 more
doaj   +1 more source

The relationship between sleep and physical activity in nonagenarians and centenarians

Geriatrics, Gerontology and Aging, 2022
OBJECTIVE: Since the relationship between physical activity and sleep quality has been poorly studied in nonagenarians and centenarians, this study sought to relate the sleep quality and physical activity in this age group.
Francielle Bonett Aguirre, Antonia Angeli Gazola, Victória Albino Furlanetto Araujo, Ângelo José Gonçalves Bós   +3 more
doaj   +1 more source

Cancer statistics for adults aged 85 years and older, 2019

Ca, 2019
Adults aged 85 years and older, the “oldest old,” are the fastest‐growing age group in the United States, yet relatively little is known about their cancer burden.
C. DeSantis, K. D. Miller, W. Dale, S. Mohile, H. Cohen, C. Leach, Ann Goding Sauer, A. Jemal, R. Siegel   +8 more
semanticscholar   +1 more source

Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response [PDF]

, 2018
Mechanoadaptation maintains bone mass and architecture; its failure underlies age-related decline in bone strength. It is unclear whether this is due to failure of osteocytes to sense strain, osteoblasts to form bone or insufficient mechanical stimulus ...
A Carriero, A Moustafa, AF Pereira, AG Robling, AG Robling, AH Ng, AI Birkhold, AI Birkhold, AM Hanson, AM Weatherholt, B Javaheri, B Javaheri, B Javaheri, B Javaheri, B Kamal, BM Willie, C Liu, C Turner, CA Schneider, CH Turner, CT Rubin, DB Burr, DB Burr, DM Cullen, E Smith, ER Spector, EW Helge, F Bini, G Ducher, H Razi, J Wergedal, JR Mosley, JR Mosley, K Deere, K Deere, KC Lee, KE Poole, KJ Jepsen, LB Meakin, LE Lanyon, LE Lanyon, LE Lanyon, LE Lanyon, M Doube, M Schaffler, M Steiner, MD Brodt, MD Willinghamm, ME Lynch, MM Shimano, N Holguin, N Holguin, N Holguin, N Lara-Castillo, P Lind, P Sztefek, R DeSouza, RH Routh, RL Souza De, SM Millard, SM Ponik, T Jämsä, TC Lee, TK Patel, Y Umemura   +64 more
core   +3 more sources

What is Aging? [PDF]

Frontiers in Genetics, 2012
In 1991, the book Evolutionary Biology of Aging offered the following definition of aging: a persistent decline in the age-specific fitness components of an organism due to internal physiological deterioration (Rose, 1991). This definition has since been used by others a number of times.
Rose, Michael R, Flatt, Thomas, Graves, Joseph L, Greer, Lee F, Martinez, Daniel E, Matos, Margarida, Mueller, Laurence D, Reis, Robert J Shmookler, Shahrestani, Parvin   +8 more
openaire   +7 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice

Aging Cell, 2018
Microglia, the resident immune cell of the brain, can be eliminated via pharmacological inhibition of the colony‐stimulating factor 1 receptor (CSF1R).
M. Elmore, Lindsay A. Hohsfield, E. Kramár, Lilach Soreq, Rafael J. Lee, S. T. Pham, A. Najafi, Elizabeth E. Spangenberg, M. Wood, B. West, K. Green   +10 more
semanticscholar   +1 more source

Whole body vibration training and its application to age-related performance decrements:an exploratory analysis [PDF]

, 2015
Middle age is associated with a pronounced decline in power and flexibility. Whilst whole body vibration training (WBVT) improves performance in a range of populations, whether WBVT can improve muscle power and flexibility in a middle-aged population is ...
Babraj, John, Cobley, James N., Griffiths, Katie, Hawkey, Adam   +3 more
core   +3 more sources

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Income and Poverty Among Older Americans in 2008 [PDF]

, 2007
[Excerpt] Older Americans are an economically diverse group. In 2008, the median income of individuals aged 65 and older was $18,208 but incomes varied widely around this average.
Purcell, Patrick
core   +6 more sources