Results 171 to 180 of about 7,426,653 (346)

Interleukin‐6 neutralization ameliorates symptoms in prematurely aged mice [PDF]

open access: gold, 2021
Stefano Squarzoni   +17 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Depressive Symptoms and One Year Mortality among Elderly Patients Discharged from a Rehabilitation Ward after Orthopaedic Surgery of the Lower Limbs

open access: yesBehavioural Neurology, 2010
Fabio Guerini   +4 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

The impact of aging of solar cells on the performance of photovoltaic panels

open access: gold, 2021
Sofia Antunes Alves dos Santos   +3 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The acceptability of participating in data linkage research: research with older Australians

open access: yesAustralian and New Zealand Journal of Public Health, 2018
Stephanie L. Harrison   +4 more
doaj   +1 more source

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