Results 191 to 200 of about 7,426,653 (346)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Senescent Cells Involved in Deterioration of Bone Microstructure by High-Frequency Parathyroid Hormone 1-34 Administration and Bone Loss. [PDF]

Aging Cell
Bun M, Ukon Y, Ikuta M, Kitahara T, Furuichi T, Hirai H, Tateiwa D, Kanie Y, Furuya M, Fujimori T, Otsuru S, Okada S, Kaito T.   +12 more
europepmc   +1 more source

Ageing [PDF]

Nature, 2010
openaire   +2 more sources

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source

Challenges and Accomplishments of Overseas-Trained Nurses in Australian Aged Care: A Qualitative Study of Indian Nurses' Experiences. [PDF]

J Nurs Manag
Joseph B, Joseph S, Emmanuel R.
europepmc   +1 more source

Social and Economic Problems of the Aged [PDF]

, 1966
Suedkamp, Wilbur F.
core   +1 more source

MABAL: a Novel Deep-Learning Architecture for Machine-Assisted Bone Age Labeling [PDF]

, 2018
Simukayi Mutasa, Peter Chang, Carrie Ruzal‐Shapiro, Rama S. Ayyala   +3 more
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

The Potential of Ectoine as a Brain Anti-Aging Agent in Rat Model of D-Galactose-Accelerated Aging May Be Mediated Through Crosstalk Between Redox/Mitochondrial Homeostasis/Autophagic/Apoptotic Pathways. [PDF]

Mol Neurobiol
Alsenousy AHA, Bakir MB, Zommara MS, Edres HA, Darwish WS, Eid RMHM, Kamel MA.   +6 more
europepmc   +1 more source

Sound credit scores and financial decisions despite cognitive aging

, 2014
Ye Li, Jie Gao, A. Zeynep Enkavi, Lisa Zaval, Elke U. Weber, Eric J. Johnson   +5 more
openalex   +1 more source