Results 251 to 260 of about 7,720,905 (351)

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Lymphatic pumping technique in mice alters blood parameters and metastatic melanoma in an age-dependent manner. [PDF]

open access: yesExp Biol Med (Maywood)
Walsh C   +11 more
europepmc   +1 more source

Ages of Ages

open access: yes
Ages of Ages is for SATB a capella choir. It is inspired by text taken from the medieval Old Hispanic chant, León 8, fol. 273: Et non deficiet ex te vir qui compleat voluntatem meam; and León 8, fol. 88v: Gloria et honor patri et filio et spiritui sancto et nunc and semper et in saecula saeculorum. An English translation is used for this piece.
openaire   +1 more source

Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats

open access: gold, 2019
Shangfu Xu   +5 more
openalex   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

RSV Prevention Products and Severe RSV-Associated Disease Among Infants.

open access: yesJAMA Netw Open
Bennett JC   +8 more
europepmc   +1 more source

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