Results 21 to 30 of about 7,081,410 (338)

Mini-review on initiatives to interfere with the propagation and clearance of alpha-synuclein in Parkinson’s disease

open access: yesTranslational Neurodegeneration, 2017
In this mini-review, we summarize recent findings relating to the prion-like propagation of α-synuclein (α-syn) and the development of novel therapeutic strategies to target synucleinopathy in Parkinson’s disease (PD).
Daniel Kam Yin Chan   +4 more
doaj   +1 more source

Comparing clinico-demographics and neuropsychiatric symptoms for immigrant and non-immigrant aged care residents living with dementia: a retrospective cross-sectional study from an Australian dementia-specific support service

open access: yesBMC Geriatrics, 2023
Background Neuropsychiatric symptoms of dementia such as agitation and aggression are common in people living with dementia. The presentation of neuropsychiatric symptoms is influenced by the cultural background of people living with dementia.
Pelden Chejor   +5 more
doaj   +1 more source

Chemical restraint as behavioural euthanasia: case studies from the Royal Commission into Aged Care Quality and Safety

open access: yesBMC Geriatrics, 2023
Background The prescription of psychotropic medication to older people living with dementia in residential aged care has become an increasing concern.
Patricia Cain   +2 more
doaj   +1 more source

A study protocol for the development of a multivariable model predicting 6- and 12-month mortality for people with dementia living in residential aged care facilities (RACFs) in Australia

open access: yesDiagnostic and Prognostic Research, 2020
Background For residential aged care facility (RACF) residents with dementia, lack of prognostic guidance presents a significant challenge for end of life care planning.
Ross Bicknell   +3 more
doaj   +1 more source

Changing stroke mortality trends in middle-aged people: an age-period-cohort analysis of routine mortality data in persons aged 40 to 69 in England [PDF]

open access: yes, 2010
Background: In the UK, overall stroke mortality has declined. A similar trend has been seen in coronary heart disease, although recent reports suggest this decline might be levelling off in middle-aged adults.
Dey, Maria Paola   +4 more
core   +1 more source

Prevalence and incidence of cancer related lymphedema in low and middle-income countries: a systematic review and meta-analysis

open access: yesBMC Cancer, 2020
Background Little is known about the prevalence and incidence in low and middle-income countries (LMICs) of secondary lymphedema due to cancer. The purpose of the study is to estimate the prevalence and incidence in LMICs of secondary lymphedema related ...
Eric Torgbenu   +4 more
doaj   +1 more source

The combined molecular adjuvant CASAC enhances the CD8+ T cell response to a tumor-associated self-antigen in aged, immunosenescent mice [PDF]

open access: yes, 2015
BACKGROUND: Ineffective induction of T cell mediated immunity in older individuals remains a persistent challenge for vaccine development. Thus, there is a need for more efficient and sophisticated adjuvants that will complement novel vaccine strategies ...
Amofah, E   +10 more
core   +3 more sources

Aging [PDF]

open access: yesKorean Journal of Audiology, 2013
Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression
Park, Dong Choon, Yeo, Seung Geun
openaire   +2 more sources

Use of an Activity Monitor and GPS Device to Assess Community Activity and Participation in Transtibial Amputees

open access: yesSensors, 2014
This study characterized measures of community activity and participation of transtibial amputees based on combined data from separate accelerometer and GPS devices.
Brenton Hordacre   +2 more
doaj   +1 more source

Incorporating Safety and Quality Measures Into Australia’s Activity-Based Funding of Public Hospital Services

open access: yesHealth Services Insights, 2023
In a bid to improve quality of care, numerous countries have incorporated rewards and penalties into the funding and pricing of hospital services. This paper outlines recent advances in Australia to incorporate financial penalties for hospital acquired ...
Samuel B. G. Webster   +4 more
doaj   +1 more source

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