Results 21 to 30 of about 7,426,653 (346)

Chemical restraint as behavioural euthanasia: case studies from the Royal Commission into Aged Care Quality and Safety

BMC Geriatrics, 2023
Background The prescription of psychotropic medication to older people living with dementia in residential aged care has become an increasing concern.
Patricia Cain, Pelden Chejor, Davina Porock   +2 more
doaj   +1 more source

Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response [PDF]

, 2018
Mechanoadaptation maintains bone mass and architecture; its failure underlies age-related decline in bone strength. It is unclear whether this is due to failure of osteocytes to sense strain, osteoblasts to form bone or insufficient mechanical stimulus ...
A Carriero, A Moustafa, AF Pereira, AG Robling, AG Robling, AH Ng, AI Birkhold, AI Birkhold, AM Hanson, AM Weatherholt, B Javaheri, B Javaheri, B Javaheri, B Javaheri, B Kamal, BM Willie, C Liu, C Turner, CA Schneider, CH Turner, CT Rubin, DB Burr, DB Burr, DM Cullen, E Smith, ER Spector, EW Helge, F Bini, G Ducher, H Razi, J Wergedal, JR Mosley, JR Mosley, K Deere, K Deere, KC Lee, KE Poole, KJ Jepsen, LB Meakin, LE Lanyon, LE Lanyon, LE Lanyon, LE Lanyon, M Doube, M Schaffler, M Steiner, MD Brodt, MD Willinghamm, ME Lynch, MM Shimano, N Holguin, N Holguin, N Holguin, N Lara-Castillo, P Lind, P Sztefek, R DeSouza, RH Routh, RL Souza De, SM Millard, SM Ponik, T Jämsä, TC Lee, TK Patel, Y Umemura   +64 more
core   +4 more sources

Mini-review on initiatives to interfere with the propagation and clearance of alpha-synuclein in Parkinson’s disease

Translational Neurodegeneration, 2017
In this mini-review, we summarize recent findings relating to the prion-like propagation of α-synuclein (α-syn) and the development of novel therapeutic strategies to target synucleinopathy in Parkinson’s disease (PD).
Daniel Kam Yin Chan, Ying Hua Xu, Luke Kar Man Chan, Nady Braidy, George D. Mellick   +4 more
doaj   +1 more source

Changing stroke mortality trends in middle-aged people: an age-period-cohort analysis of routine mortality data in persons aged 40 to 69 in England [PDF]

, 2010
Background: In the UK, overall stroke mortality has declined. A similar trend has been seen in coronary heart disease, although recent reports suggest this decline might be levelling off in middle-aged adults.
Dey, Maria Paola, Leathley, Michael J, Marsden, Jenny, Sutton, Chris J, Watkins, Caroline L   +4 more
core   +1 more source

A study protocol for the development of a multivariable model predicting 6- and 12-month mortality for people with dementia living in residential aged care facilities (RACFs) in Australia

Diagnostic and Prognostic Research, 2020
Background For residential aged care facility (RACF) residents with dementia, lack of prognostic guidance presents a significant challenge for end of life care planning.
Ross Bicknell, Wen Kwang Lim, Andrea B. Maier, Dina LoGiuidice   +3 more
doaj   +1 more source

Bone health of middle-aged and older surfers [PDF]

, 2019
Purpose: Given the lack of research investigating surfing and bone health, we aimed to assess the bone mineral density (BMD) of middle-aged and older surfers.
Beck, Belinda R., Climstein, Mike, Hing, Wayne A., Pope, Rodney, Rathbone, Evelyne, Simas, Vini   +5 more
core   +1 more source

Comparing clinico-demographics and neuropsychiatric symptoms for immigrant and non-immigrant aged care residents living with dementia: a retrospective cross-sectional study from an Australian dementia-specific support service

BMC Geriatrics, 2023
Background Neuropsychiatric symptoms of dementia such as agitation and aggression are common in people living with dementia. The presentation of neuropsychiatric symptoms is influenced by the cultural background of people living with dementia.
Pelden Chejor, Mustafa Atee, Patricia Cain, Daniel Whiting, Thomas Morris, Davina Porock   +5 more
doaj   +1 more source

Use of an Activity Monitor and GPS Device to Assess Community Activity and Participation in Transtibial Amputees

Sensors, 2014
This study characterized measures of community activity and participation of transtibial amputees based on combined data from separate accelerometer and GPS devices.
Brenton Hordacre, Christopher Barr, Maria Crotty   +2 more
doaj   +1 more source

Prevalence and incidence of cancer related lymphedema in low and middle-income countries: a systematic review and meta-analysis

BMC Cancer, 2020
Background Little is known about the prevalence and incidence in low and middle-income countries (LMICs) of secondary lymphedema due to cancer. The purpose of the study is to estimate the prevalence and incidence in LMICs of secondary lymphedema related ...
Eric Torgbenu, Tim Luckett, Mark A. Buhagiar, Sungwon Chang, Jane L. Phillips   +4 more
doaj   +1 more source

The Belfast Youth Development Study (BYDS): A prospective cohort study of the initiation, persistence and desistance of substance use from adolescence to adulthood in Northern Ireland [PDF]

, 2018
Background: Substance misuse persists as a major public health issue worldwide with significant costs for society. The development of interventions requires methodologically sound studies to explore substance misuse causes and consequences. This Cohort
Higgins, Kathryn, Jordan, Julie Anne, McCann, Mark, McCartan, Claire, McLaughlin, Aisling, Percy, Andrew, Perra, Oliver   +6 more
core   +9 more sources