Results 171 to 180 of about 1,246,316 (269)

Comprehensive insights into the prescribing trends of carbamazepine, lamotrigine, lithium, and valproate in the UK Primary Care from 1995 to 2018. [PDF]

PLoS One
Samsuddin SW, Bazo-Alvarez JC, Schartau P, Petersen I.   +3 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA) in Moderate Sedation in Patients Aged 80 Years and Older. [PDF]

J Clin Med
Casalini E, Fontana M, Piro R, Ruggiero P, Taddei S, Ronzoni L, Rossi L, Facciolongo N.   +7 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Correction: Elevated gonadotropins and risk of dementia in Chinese adults aged over 80: a cross-sectional study. [PDF]

Front Aging Neurosci
Zhu Y, Tu Y, Ren C, Ke Y, Guo Q.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Mapping the Burden of Hypertension in Türkiye (2008-2022): A National Cross-Sectional Study of Nearly 100000 Adults. [PDF]

Int J Hypertens
Sakir R, Yahya D, Kocak M.
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Is health-related quality of life significantly different in very elderly patients receiving home mechanical ventilation? [PDF]

J Bras Pneumol
Machado T, Sá T, Viegas P, Roseta L, Ribeiro C.   +4 more
europepmc   +1 more source