Results 251 to 260 of about 2,584,660 (392)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Ranking the most efficient human papillomavirus vaccination strategies in low-income and lower-middle income countries: a mathematical modelling analysis. [PDF]

Lancet Glob Health
Bénard É, Drolet M, Gingras G, Laprise JF, Sabourin AA, Bloem P, Akaba H, Brotherton J, Jit M, Brisson M.   +9 more
europepmc   +1 more source

Treatment of Stage II/III Esophageal Cancer in Patients Aged 80 Years and Over

, 2017
Toshimi Chiba, Kyoko Suzuki, Tomoko Matsui, Akira Miura   +3 more
openalex   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study.

Age and Ageing, 2013
F. Landi, A. Cruz-Jentoft, R. Liperoti, A. Russo, S. Giovannini, M. Tosato, E. Capoluongo, R. Bernabei, G. Onder   +8 more
semanticscholar   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

The Role of Radiotherapy in Octogenarian Cancer Patients. [PDF]

Cancers (Basel)
Lebiedzińska A, Wasilewska-Teśluk E, Sopel A, Nawrocki S.   +3 more
europepmc   +1 more source

Baseline functional status impairment as a factor predictive of a poor benefit of ICU admission in patients aged over 80 years with severe acute respiratory syndrome coronavirus 2 infection

Nory Elhadjène, Nicolas Maillard, Claire Falandry, Jérôme Morel   +3 more
openalex   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Outcomes and safety of colonoscopy in elderly patients aged 80 years and older: a retrospective cohort study. [PDF]

PeerJ
Ding Y, Lin X.
europepmc   +1 more source