Results 101 to 110 of about 403,137 (309)
Acta Neuropathologica Communications, 2019 Hexanucleotide repeat expansions of variable size in C9orf72 are the most prevalent genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia.
Javier Morón-Oset +5 more
doaj +1 more source
Blueprint for an ageing Australia [PDF]
, 2014 This paper sets out sets out the steps for Australia to take to ensure that ageing is an asset, not a ...
core
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
, 2019 What does it mean to age well? This important new book redefines what ‘successful’ ageing means, challenging the idea that physical health is the only criteria to gauge the ageing process and that an ageing population is necessarily a burden upon society.
Stephens, Christine, Breheny, Mary
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Medical Risk Factors for Dementia; A Case-Control Study
Iranian Rehabilitation Journal, 2019 Objectives: Dementia is the fifth cause of death in older adults with the most significant financial, social, and caring burden on health systems across the world.
Hossein Ghasemzadeh +5 more
doaj
BMC Public HealthBackground Recreational parks can play a significant role in older people’s health, with emerging evidence suggesting that changes in the physical environment, such as refurbishments of local parks, can increase park visitations and physical activity ...
Pazit Levinger +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source