Results 281 to 290 of about 929,250 (364)

Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances. [PDF]

open access: yesSignal Transduct Target Ther
Jiang Q   +10 more
europepmc   +1 more source

Real‐world genomic landscape of colon and rectal cancer

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 674-685, April 2025.
We confirmed enrichment of RTK alterations in patients with RAS/BRAF‐wt tumors and of PI3K pathway alterations in RAS/BRAF‐altered tumors with 51 982 real‐world tissue comprehensive genomic profiling (CGP) samples in CRC. In a subset of 140 patients with both tissue and liquid results, the sensitivity of liquid for results found by tissue was 100% when
Markus Schulze   +7 more
wiley   +1 more source

Making the Right to Oral Health a Reality for Older Adults. [PDF]

open access: yesInt Dent J
Fukai K   +5 more
europepmc   +1 more source

FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 622-633, April 2025.
We explored the role of FSH on the synovium and found that FSH was able to mediate the development of osteoarthritis by acting on the FSH receptor (FSHR) to promote the production and release of inflammatory factors through the activation of the NFκB signaling pathway. Previous studies have suggested that women with higher follicle‐stimulating hormone (
Yu Chen   +6 more
wiley   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

open access: yesFEBS Open Bio, Volume 15, Issue 5, Page 867-884, May 2025.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano   +16 more
wiley   +1 more source

The Ageing Behavior of Cu-4 wt%Ti Alloy

open access: bronze, 1967
Kazuo Saito   +2 more
openalex   +2 more sources

Could life story work support relational autonomy in advance care planning? Stories from the EARLI project. [PDF]

open access: yesAustralas J Ageing
Karusoo-Musumeci A   +6 more
europepmc   +1 more source

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