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Epigenomic and transcriptomic germ-free ageing atlas reveals sterile inflammation as an intrinsic ageing feature

Nijen Twilhaar W, Chang J, Terooatea TW, Yabukami H, Kato S, Hetherington N, Satoh-Takayama N, Ahmadi A, Hsieh T, Jeyamohan P, Kageyama T, Lan YJ, Kadono-Maekubo N, Maeda S, Miyajima Y, Mochizuki M, Motomura Y, Nakanishi Y, Rother N, Tahara U, Takeno N, Tsutsui K, Barcelo MV, Wang H, Amagai M, Fujiwara H, Hon CC, Matsui T, Moro K, Nourshargh S, Ohno H, Minoda A.   +31 more
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Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

Nature Reviews Molecular Cell Biology, 2021
Simon Alberti, Anthony A Hyman
exaly   +2 more sources

DNA methylation-based biomarkers and the epigenetic clock theory of ageing

Nature Reviews Genetics, 2018
Steve Horvath, Kenneth Raj
exaly   +2 more sources

Ageing as a risk factor for neurodegenerative disease

Nature Reviews Neurology, 2019
Yujun Hou, Xiuli Dan, Mansi Babbar
exaly   +2 more sources

The proteostasis network and its decline in ageing

Nature Reviews Molecular Cell Biology, 2019
Mark Hipp, Prasad Kasturi, F Ulrich Hartl   +2 more
exaly   +2 more sources

Mitochondria in Health, Disease, and Ageing.

Physiological Reviews, 2023
Mitochondria are well-known as organelles responsible for the maintenance of cellular bioenergetics through the production of ATP. While oxidative phosphorylation may be their most important function, mitochondria are also integral for the synthesis of ...
J. Harrington, S. Ryter, M. Plataki, David R. Price, A. Choi   +4 more
semanticscholar   +1 more source