Results 181 to 190 of about 9,158 (215)

Associations of urinary incontinence, absorbent product use, and confidence gained from absorbent product use with perceived ageism in later adulthood. [PDF]

Gerontologist
Brady SS, Arguedas A, Huling JD, Hellemann G, Lewis CE, Jacobs DR, Fok CS, Van Den Eeden SK, Markland AD.   +8 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Interaction between perceived ageism and poor sleep quality on frailty among community-dwelling older adults: a cross-sectional study. [PDF]

BMC Geriatr
Ye B, Li Y, Chen L, Gong K, Gao J.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

There, but not there: older people in anti-ageism interventions. [PDF]

Gerontologist
Morrow-Howell N, Li S, Li A, Wininger C, Galucia N, Carpenter BD.   +5 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Older Adult Care Career Intention and Associated Factors Among Higher Vocational College Students: A Cross-Sectional Study. [PDF]

Nurs Open
Liu B, Ying Y, Sun N, Li L, Wang F, Xu Z, Zhou H, Zhou S.   +7 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Older adults' report of fight-or-flight and other acute stress responses to ageism and linkages to health. [PDF]

Aging Ment Health
Allen JO, Qin W, Kiefer M, Cunnyngham KE.   +3 more
europepmc   +1 more source

Ableism, ageism, and other biases in healthcare: The impact on young adult patients. [PDF]

Health Care Transit
Rosewater JT, Dave S, Didier M, Melton K.   +3 more
europepmc   +1 more source