Results 101 to 110 of about 5,017,591 (314)
Loss of agency in apraxia [PDF]
, 2014 The feeling of acting voluntarily is a fundamental component of human behavior and social life and is usually accompanied by a sense of agency. However, this ability can be impaired in a number of diseases and disorders.
GALLI, GIULIA, PAZZAGLIA, Mariella
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Skills Funding Agency Delivery Plan 2010/11 [PDF]
, 2010 "This Delivery Plan sets out the way in which the Agency has responded to the priorities set out in the 'Skills Investment Strategy and Skills for Growth', as well as policy commitments outlined in 'The Coalition: Our Programme for Government' (May 2010).
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Choosing Financial Regulatory Agency Mandates [PDF]
, 2009 Outlines four approaches to dividing the responsibilities of federal financial regulatory agencies: institutional regulation, functional regulation, regulation by objective, and an integrated approach.
Charles Taylor
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A legacy handbook for manufacturing [PDF]
, 2011 Legacy Handbook reviewing emda's experience of manufacturing activity. Identifies key achievements and draws out lessons learned that may be relevant to successor bodies active in this ...
East Midlands Development Agency, EMDA
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Agency in Architecture: Reframing Criticality in Theory and Practice
Footprint, 2009 Whether critiquing the architect’s societal position and the role of the user, conceptualising the performative dimension of the architectural object, or considering the effects of theory for architecture at large, current debates in architecture ...
Isabelle Doucet, Kenny Cupers
doaj
A legacy handbook for innovation [PDF]
, 2011 Legacy Handbook reviewing emda's experience of innovation activity. Identifies key achievements and draws out lessons learned that may be relevant to successor bodies active in this ...
East Midlands Development Agency, EMDA
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