Results 71 to 80 of about 948,725 (293)

From Object to Mediator: The Agency of Documents

open access: yesProceedings from the Document Academy, 2015
This paper takes as a starting point one particular development in social theory – the concept of mediation – and applies it to the document. Central to this discussion is a conceptualisation of documents as objects, albeit one which fails if we assume ...
Sally Irvine-Smith
doaj   +1 more source

Automation in Human-Machine Networks: How Increasing Machine Agency Affects Human Agency [PDF]

open access: yesarXiv, 2017
Efficient human-machine networks require productive interaction between human and machine actors. In this study, we address how a strengthening of machine agency, for example through increasing levels of automation, affect the human actors of the networks. Findings from case studies within air traffic management, crisis management, and crowd evacuation
arxiv  

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Review: David Howarth (2000). Discourse

open access: yesForum: Qualitative Social Research, 2002
HOWARTH's book is an accessible, readable and concise overview of theories of and approaches to discourse in the human and social sciences, focusing upon LACLAU and MOUFFE's discourse theory approach.
John Cromby
doaj  

Photographs of the “Dust of the Highway”: Georgiana Goddard King’s Way of Saint James

open access: yesContemporaneity: Historical Presence in Visual Culture, 2016
This article explores the use of photography in American art historian Georgiana Goddard King’s Way of Saint James (1920), a genre-defying book on the Camino de Santiago that intertwines art history with anthropology, literature, history, geography, and ...
Annemarie Iker
doaj   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

Editorial: ‘Inter-identities' in Life, Mind, and Society

open access: yesFrontiers in Psychology, 2021
Arantza Etxeberria   +3 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

White Men Lead, Black Women Help? Benchmarking Language Agency Social Biases in LLMs [PDF]

open access: yesarXiv
Social biases can manifest in language agency. While several studies approached agency-related bias in human-written language, very limited research has investigated such biases in Large Language Model (LLM)-generated content. In addition, previous works often rely on string-matching techniques to identify agentic and communal words within texts, which
arxiv  

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