Results 41 to 50 of about 256,945 (259)

Corporate tax evasion with agency costs [PDF]

open access: yesJournal of Public Economics, 2005
This paper examines corporate tax evasion in the context of the contractual relationship between the shareholders of a firm and a tax manager who possesses private information regarding the extent of legally permissible reductions in taxable income, and who may also undertake illegal tax evasion.
Keith J. Crocker, Joel Slemrod
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

PENGHINDARAN PAJAK TERHADAP NILAI PERUSAHAAN DAN BIAYA AGENSI DENGAN TRANSPARANSI INFORMASI SEBAGAI VARIABEL PEMODERASI

open access: yesJurnal Analisis Bisnis Ekonomi, 2018
This study aims to examine the effect of tax avoidance as an independent variable to firm value and agency cost as dependent variable and transparency of information as moderating variable.
Theresa Dina Tarida   +1 more
doaj   +1 more source

DETERMINAN PENGUNGKAPAN VARIASI PERTUMBUHAN LABA ANTAR SEGMEN

open access: yesJurnal Akuntansi Kontemporer, 2020
The results of previous studies regarding the determinants of strategic revelation of differences in segmen earnings growth are still not consistent.
Natalia Christine Putri, Lodovicus Lasdi
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

AGENCY COST TO DIVIDEND PAYOUT RATIO

open access: yesJurnal Analisis Bisnis Ekonomi, 2017
Penelitian ini dilakukan untuk menguji pengaruh biaya keagenan terhadap kebijakan dividen (dividen payout ratio). Dalam hal ini, biaya keagenan diwakili oleh kepemilikan insider, kepemilikan institusional, collateralizable asset, debt to total assets ...
Nur Imam, Prasetiono Prasetiono
doaj  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Employee Stock Ownership Plans and Market Stability: A Longitudinal Analysis of Stock Price Crash Risk in China

open access: yesRisks
Reducing stock price crash risk is vital for capital market stability, particularly in emerging economies such as China. This study investigates whether Employee Stock Ownership Plans (ESOPs) can mitigate crash risk by analyzing panel data from A-share ...
Mengfei Liu, Xiyuan Jiang, Xuyan Tong
doaj   +1 more source

The social cost of adoption agencies

open access: yesInternational Review of Law and Economics, 1986
Abstract The use of adoption agencies to place adoptable children is compared with a market. The lost consumer surplus to potential adopting parents amounts to between $45 million and $1.7 billion per year. In addition, evidence is presented from follow-up studies of adoptions to indicate that social workers do a poorer job of matching parents with ...
openaire   +3 more sources

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