Results 131 to 140 of about 721,382 (297)

Bringing the Mass Media in - The Contribution of the Mass Media for Understanding Citizens’ Attitudes towards the European Union [PDF]

open access: yes
Economic considerations, identity related considerations and cueing theory are used for explaining citizens’ attitudes towards the European Union. Yet, all of this research has failed to show how elite cues on interests and identities actually reach the ...
Silke Adam
core  

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

open access: yesAdvanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong   +6 more
wiley   +1 more source

DAMPAK MEDIA, PENENTUAN AGENDA (AGENDA SETTING), DAN TEORI THE SPIRAL OF SILENCE

open access: yesWardah, 2015
The impact of media, Determination Agenda (Agenda Setting) and Theory of The Spiral Of Silence is a three-part study of the theory of Mass Communication.
Sumaina Duku
doaj  

Aproximación al hecho religioso en la agenda informativa de la prensa española [PDF]

open access: yes
The religious experience is part of the human experience and, as anything that arouses our interest, becomes an objective for mass media. The press has an agenda with mechanisms to approach issues that can become news.
Cordero Morales, Fernando
core   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

FORMAÇÃO DE AGENDA E CORRELAÇÃO DE FORÇAS POLÍTICAS: a aprovação da redução da maioridade penal na Câmara Federal

open access: yesRevista de Políticas Públicas, 2020
This article aims to analyze the approval of the reduction of the legally punishable age case in Chamber of Deputies in 2015. Received for the first time in 1993, the Proposal of Constitutional Amendment nº.
Lillian Lages Lino, Daniel Arias Vazquez
doaj  

Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice

open access: yesAdvanced Science, EarlyView.
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao   +13 more
wiley   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

open access: yesAdvanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia   +14 more
wiley   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

open access: yesAdvanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy