CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su +5 more
wiley +1 more source
Narrative strategies and interaction performance in Olympic short videos on Chinese mainstream media: evidence from the 2024 Paris Summer Olympics. [PDF]
Yi G, Wang H.
europepmc +1 more source
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang +5 more
wiley +1 more source
A Coaching-Centered Inpatient Rotation Fosters Growth Mindset and Deliberate Practice in Resident Physicians. [PDF]
Tang AJ +8 more
europepmc +1 more source
Physics‐Aware Machine‐Learning‐Driven Inverse Design of Broadband Ultra‐Open Acoustic Metamaterials
A physics‐aware machine‐learning framework enables inverse design of ultra‐open acoustic silencers by decoupling spectral and radial design spaces. The approach rapidly identifies broadband, compact, and highly ventilated architectures, while revealing hidden linear design rules that link geometry, impedance matching, and acoustic performance.
Zhiwei Yang +5 more
wiley +1 more source
Catalyzing collaboration through intentional design: the Teaming for Biomedical Digital Twin (Teaming4BDT) conference. [PDF]
Bennett LM, Xiao Z.
europepmc +1 more source
The role of the Internet in shaping news agenda: a critical analysis of the agenda-setting theory [PDF]
openaire +1 more source
Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao +10 more
wiley +1 more source
Analysis of food policymaking through a food systems lens: a review of analytical frameworks. [PDF]
Stanley I, Murrin C.
europepmc +1 more source
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao +7 more
wiley +1 more source

