Results 141 to 150 of about 11,927,890 (342)

Making Models Match: Replicating an Agent-Based Model [PDF]

Scientists have increasingly employed computer models in their work. Recent years have seen a proliferation of agent-based models in the natural and social sciences.
Uri Wilensky, William Rand
core  

Biodiversity in rubber agroforests, carbon emissions, and rural livelihoods: An agent-based model of land-use dynamics in lowland Sumatra

Environmental Modelling & Software, 2014
Rubber agroforests in the mostly deforested lowlands of Sumatra, Indonesia are threatened by conversion into monoculture rubber or oil palm plantations.
G. Villamor, Q. B. Le, U. Djanibekov, M. Noordwijk, P. Vlek   +4 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

An agent-based model of citation behavior

Applied Network Science
Whether citations objectively and reliably reflect the quality of articles and researchers is questionable. Even so, citation counts are widely used to estimate the productivity of researchers and institutions, which creates a ‘grubby’ motivation to be ...
George Chacko, Minhyuk Park, Vikram Ramavarapu, Ananth Grama, Pablo Robles-Granda, Tandy Warnow   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A Study of Tennis Tournaments by Means of an Agent-Based Model Calibrated with a Genetic Algorithm

Mathematical and Computational Applications
In this work, we study the sport of tennis, with the aim of understanding competitions and the associated quantities that determine their outcome.
Salvatore Prestipino, Andrea Rapisarda
doaj   +1 more source

Agent-based Model Construction In Financial Economic System [PDF]

The paper gives picture of enrichment to economic and financial system analysis using agent-based models as a form of advanced study for financial economic data post-statistical-data analysis and micro- simulation analysis.
Hokky Situngkir, Yohanes Surya
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Simulating Knowledge-Generation and -Distribution Processes in Innovation Collaborations and Networks [PDF]

An agent-based simulation model representing a theory of the dynamic processes involved in innovation in modern knowledge-based industries is described. The agent-based approach al-lows the representation of heterogeneous agents that have individual and ...
Andreas Pyka, Nigel Gilbert, Petra Ahrweiler   +2 more
core