Results 131 to 140 of about 11,927,890 (342)
HMAE: a high-fidelity multi-agent simulator for economic phenomenon emergence
Frontiers in PhysicsEconomic models based on multi-agents are increasingly attracting attention and can provide a new perspective for exploring the causes behind social phenomena at the individual level.
Chao Wang +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Using Hybrid Agent-Based Systems to Model Spatially-Influenced Retail Markets [PDF]
One emerging area of agent-based modelling is retail markets; however, there are problems with modelling such systems. The vast size of such markets makes individual-level modelling, for example of customers, difficult and this is particularly true where
Alison Heppenstall +2 more
core
On the Limits of Agency in Agent-based Models
International Joint Conference on Autonomous Agents and Multiagent SystemsAgent-based modeling (ABM) offers powerful insights into complex systems, but its practical utility has been limited by computational constraints and simplistic agent behaviors, especially when simulating large populations. Recent advancements in large language models (LLMs) could enhance ABMs with adaptive agents, but their integration into large ...
Ayush Chopra +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
An Agent-Based Model of Exurban Land Development [PDF]
In contrast to urban areas that are aptly characterized by a large population base and scarce land supply, exurban regions have limited households and plentiful land.
Chen, Yong +2 more
core +1 more source
A stochastic agent-based model of the SARS-CoV-2 epidemic in France
Nature Medicine, 2020 N. Hoertel +7 more
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Towards agent-based-model informed neural networks
EPJ Data ScienceIn this article, we present a framework for designing neural networks that remain consistent with the underlying principles of agent-based models. We begin by highlighting the limitations of standard neural differential equations in modeling complex ...
Nino Antulov-Fantulin
doaj +1 more source
Simulating pedestrian movement in dynamic environments
Cybergeo, 2010 Agent-based simulation offers multiple advantages when dealing with complex phenomena like pedestrian movement, characterised by a possibly large number of locally interacting entities.
Arnaud Banos, Angèle Charpentier
doaj +1 more source