Results 121 to 130 of about 694,255 (290)

Agent-Oriented Modelling and Simulation for Robotic Based Predator Control

open access: yesJOIV: International Journal on Informatics Visualization
Agent-oriented modeling (AOM) is a methodology that can develop complex tasks that involve multi-agent system development, such as robotic systems. There are still insufficient studies on how Agent-Oriented Modelling benefits robotic development.
Yee Wee Chieh Andy   +3 more
doaj   +1 more source

Multi-level agent-based modeling with the Influence Reaction principle

open access: yes, 2012
This paper deals with the specification and the implementation of multi-level agent-based models, using a formal model, IRM4MLS (an Influence Reaction Model for Multi-Level Simulation), based on the Influence Reaction principle.
Jolly, Daniel, Morvan, Gildas
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Tools of the Trade: A Survey of Various Agent Based Modeling Platforms [PDF]

open access: yes
Agent Based Modeling (ABM) toolkits are as diverse as the community of people who use them. With so many toolkits available, the choice of which one is best suited for a project is left to word of mouth, past experiences in using particular toolkits and ...
Cynthia Nikolai, Gregory Madey
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Large language models empowered agent-based modeling and simulation: a survey and perspectives

open access: yesHumanities & Social Sciences Communications
Agent-based modeling and simulation have evolved as a powerful tool for modeling complex systems, offering insights into emergent behaviors and interactions among diverse agents.
Chen Gao   +7 more
doaj   +1 more source

Making Models Match: Replicating an Agent-Based Model [PDF]

open access: yes
Scientists have increasingly employed computer models in their work. Recent years have seen a proliferation of agent-based models in the natural and social sciences.
Uri Wilensky, William Rand
core  

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