Results 121 to 130 of about 605,883 (210)

BIWT: a bioinformatics walkthrough for embedding spatial multiomics in agent-based models for virtual cells. [PDF]

Bioinformatics
Bergman DR, Johnson JAI, Naji M, Booth M, Lima da Rocha H, Deshpande A, Sidiropoulos DN, Lopez-Vidal T, Heiland R, Kagohara LT, Anders RA, Zheng L, Jaffee EM, Stein-O'Brien G, Macklin P, Fertig EJ.   +15 more
europepmc   +1 more source

Feedback Loops in Opinion Dynamics of Agent-Based Models with Multiplicative Noise. [PDF]

Entropy (Basel), 2022
Djurdjevac Conrad N, Köppl J, Djurdjevac A.   +2 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Generalized Stable Population and Agent-Based Models of Phenotypic Transmission in Human Populations, with an Application to Body Size. [PDF]

Hum Hered
Aldea N, García-Aguirre A, Beltrán-Sánchez H, Daza S, Palloni A.   +4 more
europepmc   +1 more source

Delayed skeletal muscle repair following inflammatory damage in simulated agent-based models of muscle regeneration. [PDF]

PLoS Comput Biol, 2023
Khuu S, Fernandez JW, Handsfield GG.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Astrocyte Reprogramming Drives Tumor Progression and Chemotherapy Resistance in Agent-Based Models of Breast Cancer Brain Metastases. [PDF]

Bull Math Biol
Kaur R, Barker-Clarke R, Dhawan A.
europepmc   +1 more source

Importance of interindividual interactions in eco-evolutionary population dynamics: The rise of demo-genetic agent-based models. [PDF]

Evol Appl, 2022
Lamarins A, Fririon V, Folio D, Vernier C, Daupagne L, Labonne J, Buoro M, Lefèvre F, Piou C, Oddou-Muratorio S.   +9 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Leveraging agent-based models and deep reinforcement learning to predict taxis in cell migration. [PDF]

NPJ Syst Biol Appl
Camacho-Gomez D, Sentiero R, Ventre M, Garcia-Aznar JM.   +3 more
europepmc   +1 more source