A study of the molecular interactions of hemoglobin with diverse classes of therapeutic agents
Cezara Zăgrean-Tuza +3 more
openalex +1 more source
Insecticidal Effects of Some Biological Agents on the Gypsonoma dealbana (Lepidoptera) and Hyphantria cunea (Lepidoptera) [PDF]
, 2000 Smail Demir . +3 more
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A Perspective on Software Intelligence for Autonomous Transformations in Biomedical Data and Knowledge. [PDF]
Learn Health SystNavale V.
europepmc +1 more source
Parkia javanica Edible Pods Reveal Potential as an Anti-Diabetic Agent: UHPLC-QTOF-MS/MS-Based Chemical Profiling, In Silico, In Vitro, In Vivo, and Oxidative Stress Studies [PDF]
Alekhya Sarkar +8 more
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Sequential therapy with bevacizumab and epidermal growth factor receptor-directed agents for metastatic colorectal carcinoma: A retrospective, registry-based analysis [PDF]
, 2017 Tomáš Büchler +12 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source