Results 61 to 70 of about 1,765,270 (268)

Arene difunctionalization through an acyl-inserting Smiles rearrangement enabled by N-heterocyclic carbene catalysis

Nature Communications
Arene difunctionalization offers a powerful strategy for the simultaneous installation of two functional groups in a single step. Despite recent advances, ipso/para-selective arene transformations remain underdeveloped.
Qing-Zhu Li, Yan-Qing Liu, Long-Hai Hong, Ting Qi, Mei-Hao He, Peng-Tao Wang, Xin-Xin Kou, Jun-Long Li   +7 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Agents of discovery

SciPost Physics
The substantial data volumes encountered in modern particle physics and other domains of fundamental physics research allow (and require) the use of increasingly complex data analysis tools and workflows. While the use of machine learning (ML) tools for data analysis has recently proliferated, these tools are typically special-purpose algorithms that ...
Sascha Diefenbacher, Anna Hallin, Gregor Kasieczka, Michael Krämer, Anne Lauscher, Tim Lukas   +5 more
openaire   +2 more sources

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Evaluating the Readability of Patient‐Facing Online Educational Materials for Pediatric Leukemia and Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Together, leukemia and lymphoma account for 38.7% of newly diagnosed pediatric cancer cases in the United States each year. Many caregivers utilize online resources to inform medical health decisions. Understanding the readability of these materials is critical to ensuring comprehensible patient education.
Chloe Strege, Simone Intriago Tito, Courtney Popp, William C. Miller, Cindy Eide, Christen Ebens, Jakub Tolar   +6 more
wiley   +1 more source

Total Syntheses and Antibacterial Studies of Natural Isoflavones: Scandenone, Osajin, and 6,8-Diprenylgenistein

Molecules
Isoflavones are a class of natural products that exhibit a wide range of interesting biological properties, including antioxidant, hepatoprotective, antimicrobial, and anti-inflammatory activities. Scandenone (1), osajin (2), and 6,8-diprenylgenistein (3)
Hongbo Dong, Yufei Che, Xingtong Zhu, Yi Zhong, Jiafu Lin, Jian Wang, Weihong Du, Tao Song   +7 more
doaj   +1 more source

Agents and the UML: A Unified Notation for Agents and Multi-agent Systems? [PDF]

, 2002
Over the last few years, agent-oriented software engineering has promoted the adoption of agents as a first-class paradigm for software engineering in research and industrial development. Agents have been used in research development for more than twenty years, while they still do not find complete acceptance in industrial settings.
Bernhard Bauer 0001, Federico Bergenti, Philippe Massonet, James Odell   +3 more
openaire   +3 more sources

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source

OPACA: Toward an Open, Language- and Platform-Independent API for Containerized Agents

IEEE Access
While multi-agent frameworks can provide many advanced features, they often suffer from not being able to seamlessly interact with the outside world, e.g., with web-services or other multi-agent frameworks.
Benjamin Acar, Tobias Kuster, Oskar F. Kupke, Robert K. Strehlow, Marc Guerreiro Augusto, Fikret Sivrikaya, Sahin Albayrak   +6 more
doaj   +1 more source