Results 61 to 70 of about 537,417 (301)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Going beyond BDI for agent-based simulation

open access: yesJournal of Information and Telecommunication, 2019
Research in multi-agent systems has resulted in agent programming languages and logics that are used as a foundation for engineering multi-agent systems.
John Bruntse Larsen
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Manifesto da ciência social computacional

open access: yesMediações: Revista de Ciências Sociais, 2013
A crescente integração da tecnologia em nossas vidas criou volumes sem precedentes de dados sobre o comportamento cotidiano da sociedade. Esses dados abrem novas oportunidades para se trabalhar em direção a um entendimento quantitativo dos sistemas ...
Rosaria Conte   +13 more
doaj  

Current Trends in Simheuristics: from smart transportation to agent-based simheuristics [PDF]

open access: yes, 2018
Simheuristics extend metaheuristics by adding a simulation layer that allows the optimization component to deal efficiently with scenarios under uncertainty.
Estrada-Moreno, Alejandro   +4 more
core  

Projective simulation for artificial intelligence [PDF]

open access: yes, 2012
We propose a model of a learning agent whose interaction with the environment is governed by a simulation-based projection, which allows the agent to project itself into future situations before it takes real action.
Andy Clark   +22 more
core   +3 more sources

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

Bottom-up ecology: an agent-based model on the interactions between competition and predation

open access: yesLetters in Biomathematics, 2016
We developed an agent-based computer model of an ecosystem to predict interactions of competition and predation. In our simulations of the model, the effects of the ‘Gause law’ emerged as the results of population fluctuations and a large number of ...
Istvan Karsai   +2 more
doaj   +1 more source

Agent-based cloud simulation model for resource management

open access: yesJournal of Cloud Computing: Advances, Systems and Applications, 2023
Driven by the successful service model and growing demand, cloud computing has evolved from a moderate-sized data center consisting of homogeneous resources to a heterogeneous hyper-scale computing ecosystem.
Dapeng Dong
doaj   +1 more source

Agent Based Traffic Signals Regulating Flow On a Basic Grid [PDF]

open access: yes, 2003
A simulation study on traffic light optimisation with agent-based behaviour of the traffic ...
Brockfeld, Elmar   +2 more
core  

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